Results 251 to 260 of about 18,059 (296)

Overview of Ticlopidine’s Development

1993
The discovery and development of a new molecule imply the interplay of chance, audacity, and challenge, as well as lessons from failures and difficulties in reaching scientific and medical recognition of therapeutic progress. Persistent efforts and a consistent preclinical and clinical program should sustain the 10- to 15-year endeavor needed for ...
Edouard Panak, Monique Verry
openaire   +2 more sources

Ticlopidine inhibits phenytoin clearance

Clinical Pharmacology & Therapeutics, 1999
Because cases of phenytoin toxicity during concomitant ticlopidine therapy have been reported, we investigated the effects of multiple doses of ticlopidine on phenytoin pharmacokinetics in six patients receiving phenytoin monotherapy. Two steady-state dosing rate and serum phenytoin minimum concentration (Cmin) pairs were obtained for each patient ...
David A. Flockhart, Stephen Donahue, Darrell R. Abernethy   +2 more
openaire   +3 more sources

Ticlopidine

The Journal of Drug Evaluation, 2004
Petcharat Dusitanond, Graeme J Hankey
openaire   +1 more source

Elucidating the interaction of ticlopidine with serum albumin and its role in bilirubin displacement in vitro

Journal of Biomolecular Structure and Dynamics, 2019
S. Afrin, Y. Rahman, Mohammad Tabish
semanticscholar   +1 more source

Electrochemical behavior of ticlopidine and detection of ethanol based on Hemoglobin/Ticlopidine/Titanium oxide NPs nanobiocomposite modified electrode

, 2020
Nader Amini, A. Maleki
semanticscholar   +1 more source

Pharmacology of Ticlopidine: A Review

Seminars in Thrombosis and Hemostasis, 1989
Andre Bernat, Denis Delebassee, Gheslain Defreyn, Jean-Pierre Maffrand   +3 more
openaire   +3 more sources

A comparative biophysical and in-silico studies on the interactions of ticlopidine hydrochloride with two serum albumins

Journal of Chemical Thermodynamics, 2019
S. Khatun, Riyazuddeen, G. Rabbani
semanticscholar   +1 more source

Ticlopidine and Thrombocytopenia

New England Journal of Medicine, 1990
Kawazoe N, Koshiro Fukiyama, Yoshida T, Shuichi Takishita   +3 more
openaire   +2 more sources

Ticlopidine-Induced Phenytoin Toxicity

Annals of Pharmacotherapy, 1998
OBJECTIVE: To report a probable case of ticlopidine-induced phenytoin toxicity. CASE SUMMARY: A 72-year-old man suddenly developed combative behavior, refused to leave his room, stopped eating, and began falling to the floor 6 weeks after being given ticlopidine.
openaire   +3 more sources

Molecular spectroscopic and thermodynamic studies on the interaction of anti-platelet drug ticlopidine with calf thymus DNA.

Spectrochimica Acta Part A - Molecular and Biomolecular Spectroscopy, 2017
S. Afrin, Y. Rahman, Tarique Sarwar, M. Husain, Abad Ali, Shamsuzzaman, Mohammad Tabish   +6 more
semanticscholar   +1 more source