Results 161 to 170 of about 955,139 (390)

Development of Granzyme A Turn‐ON Fluorescent Activity‐Based Probes

open access: yesChemBioChem, EarlyView.
A quenched activity‐based probe, featuring the Ile–Gly–Asn–Arg recognition sequence, a phenyl phosphinate ester warhead, and a near‐infrared sulfo‐Cy5/QSY21 fluorophore/quencher pair, generates a fluorescence signal only upon reaction with active granzyme A (GzmA). With its high reactivity, selectivity, and cell permeability, this turn‐ON probe enables
Sebastian M. Malespini   +2 more
wiley   +1 more source

Morbilidad percibida por pobladores del Bañado Sur previa a la implementación de la Vigilancia Comunitaria del Síndrome Febril Agudo, utilizando las Tecnologías de la Información y Comunicación (TICs)

open access: yesMemorias del Instituto de Investigaciones en Ciencias de la Salud, 2011
El Ministerio de Salud Pública y Bienestar Social conjuntamente con la Universidad Nacional de Asunción, con el apoyo técnico de la Universidad del País Vasco de España, han desarrollado un sistema de vigilancia comunitaria para Síndrome Febril Agudo ...
Margarita Samudio   +8 more
doaj  

Competitividad y asimilación de tecnologías de la información y la comunicación (TIC) en pequeños productores de agricultura protegida en Guanajuato, México

open access: diamond, 2020
Claudia Rodríguez Lemus   +4 more
openalex   +1 more source

UHPLC‐MSE Insights Into Extrusion‐Driven Changes in Wheat Phenolics and Their Bioaccessibility

open access: yesCereal Chemistry, EarlyView.
ABSTRACT Background and Objectives This study evaluated the impact of thermoplastic extrusion (wheat snack, WS) and cold extrusion followed by cooking (wheat pasta, WP) on phenolic compounds (PC) in two Brazilian wheat genotypes, commercially classified by gluten strength (ORS Agile, strong; ORS Vintecinco, weak).
Renata Marenda Ferreira   +5 more
wiley   +1 more source

Unlocking Biomolecule Modification with Light‐Promoted Photocatalyst‐Free Approaches: Current Tools, Challenges, and Perspectives

open access: yesChemistryEurope, EarlyView.
This Perspective focuses on photocatalyst‐free, photoinduced modifications of biomolecules, emphasizing transformations mediated by electron donor–acceptor complexes. Mechanistic aspects, current limitations, and future opportunities are discussed, providing insight into the field of bioconjugation.
Milene Hornink   +3 more
wiley   +1 more source

Mn2+ Complex of a Fluorinated CDTA‐Derivative: Stability, Inertness, and Paramagnetic 1H, 17O, and 19F Relaxation Properties

open access: yesChemistry – A European Journal, EarlyView.
The fluorinated CDTA‐bisamide derivative ligand, L2, forms a stable and highly inert complex with Mn2+. MnL2 has one inner sphere water coordinated to the central metal ion, hence good proton relaxivity, and the paramagnetic metal ion induces important acceleration of 19F relaxation, provides good signal‐to‐noise ratios on 19F phantom UTE MR images ...
Zoltán Garda   +4 more
wiley   +1 more source

Neuralgia del trigémino: comportamiento en pacientes atendidos en el Hospital “Abel Santamaría Cuadrado”, años 2006-2011

open access: yesUniversidad Médica Pinareña, 2012
La neuralgia del trigémino constituye una enfermedad que aunque no es de elevada incidencia reviste un gran interés por su repercusión en la calidad de vida de los pacientes que la padecen.
Mallen Martínez Rodríguez   +3 more
doaj  

Development of New Benzo[b]Thiophene‐2‐Carboxamide Derivatives as Advanced Glycation End‐Products Receptor (RAGE) Antagonists

open access: yesChemMedChem, EarlyView.
A streamlined Ullmann‐Goldberg strategy enabled the synthesis of benzo[b]thiophene‐2‐carboxamides, promising ligands of the pro‐inflammatory RAGE receptor involved in inflammaging and age‐related diseases. LC‐MS, NMR, X‐ray and DFT studies elucidated the copper‐catalyzed mechanism. The lead compound, 3t’, shows inhibitory activity on the sRAGE/AGE2‐BSA
Lisa Bonin   +10 more
wiley   +1 more source

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