Results 41 to 50 of about 925,108 (377)
Results in Chemistry, 2023 Nitrogen and sulphur containing heterocyclic moieties have been found to possess extensive studies owing to their biological properties. Reporting herein the design, synthesis and spectral characterization of novel benzothiophene substituted pyrazolines.
Shivani N. Tandel +2 more
doaj
Frontiers in Neurology, 2021 The development of the complex clinical picture of motor and vocal tics in children and adolescents with Tourette syndrome (TS) must be paralleled by changes in the underlying pathophysiology.
Aribert Rothenberger +3 more
doaj +1 more source
Merging the Pathophysiology and Pharmacotherapy of Tics
Tremor and Other Hyperkinetic Movements, 2018 Background Anatomically, cortical-basal ganglia-thalamo-cortical (CBGTC) circuits have an essential role in the expression of tics. At the biochemical level, the proper conveyance of messages through these circuits requires several functionally ...
Farhan Augustine, H. Singer
semanticscholar +1 more source
Thalamic Local Field Potentials Are Related to Long-Term DBS Effects in Tourette Syndrome
Frontiers in Neurology, 2021 Background: Local field potential (LFP) recordings helped to clarify the pathophysiology of Tourette syndrome (TS) and to define new strategies for deep brain stimulation (DBS) treatment for refractory TS, based on the delivery of stimulation in ...
Sara Marceglia +9 more
doaj +1 more source
A Bayesian account of the sensory-motor interactions underlying symptoms in Tourette syndrome [PDF]
, 2019 Tourette syndrome is a hyperkinetic movement disorder. Characteristic features include tics, recurrent movements that are experienced as compulsive and “unwilled”; uncomfortable premonitory sensations that resolve through tic release; and often, the ...
Anil K. Seth +6 more
core +2 more sources
Tic Phenomenology and Tic Awareness in Adults With Autism [PDF]
Movement Disorders Clinical Practice, 2015 ABSTRACT Background: Tics are common in people with autism spectrum disorder (ASD). However, their phenomenology and characteristics have not been studied in detail. Methods: Based on video sequences of 21 adults with ASD without intellectual disability and 16 adults with Gilles de la Tourette syndrome (GTS), tic severity, tic repertoires, and tic ...
Veit Roessner +9 more
openaire +3 more sources
Melanoma-initiating cells exploit M2 macrophage TGFβ and arginase pathway for survival and proliferation [PDF]
, 2014 International audienceM2 macrophages promote tumor growth and metastasis, but their interactions with specific tumor cell populations are poorly characterized.
Abastado, Jean-Pierre +10 more
core +5 more sources
Tic Suppression in Children With Recent-Onset Tics Predicts 1-Year Tic Outcome
Journal of Child Neurology, 2019 Successful voluntary tic suppression is a key component of the behavioral interventions that are used to treat tic disorders. This study aimed to examine tic suppression in children with recent-onset tics and determine whether the capacity to suppress ...
Soyoung Kim +7 more
semanticscholar +1 more source
Reward enhances tic suppression in children within months of tic disorder onset
Developmental Cognitive Neuroscience, 2015 Tic disorders are childhood onset neuropsychiatric disorders characterized by motor and/or vocal tics. Research has demonstrated that children with chronic tics (including Tourette syndrome and Chronic Tic Disorder: TS/CTD) can suppress tics ...
Deanna J. Greene +5 more
doaj +1 more source
The role of oxidative stress in antipsychotics induced ovarian toxicity [PDF]
, 2017 This study tested the hypothesis that oxidative stress could be an underlying mechanism for APs-induced ovarian cytotoxicity and reproductive dysfunction. Rat ovarian theca interstitial cells (TICs) were isolated and treated with four APs [chlorpromazine
Aggour, Amal Misbah +4 more
core +2 more sources