Results 41 to 50 of about 46,799 (263)

Thalamic Local Field Potentials Are Related to Long-Term DBS Effects in Tourette Syndrome

Frontiers in Neurology, 2021
Background: Local field potential (LFP) recordings helped to clarify the pathophysiology of Tourette syndrome (TS) and to define new strategies for deep brain stimulation (DBS) treatment for refractory TS, based on the delivery of stimulation in ...
Sara Marceglia, Sara Marceglia, Marco Prenassi, Marco Prenassi, Tommaso F. Galbiati, Mauro Porta, Edvin Zekaj, Edvin Zekaj, Alberto Priori, Domenico Servello   +9 more
doaj   +1 more source

Modulation of miR‐23b Wnt/β‐catenin Axis Strengthens Endothelial Barrier Properties

Advanced Science, EarlyView.
Early blood‐brain barrier (BBB) disruption contributes to stroke and CNS disease pathology. miR‐23b was identified as a regulator of BBB integrity in brain endothelial cells. Inhibition of miR‐23b enhanced barrier‐associated properties, promoted repair‐related signaling, and reduced BBB leakage in experimental stroke models, supporting further ...
Victor Anthony Martinez, Rose E. Presby, Sara Nakanishi, Pallavi Gaur, Ugur Akcan, Johannes Daugaard Krog, Iben Daugaard Krog, Lipi Das, David S. Johnson, Danny Jamoul, Douglas Jury, Brian Lawson, Jacob Körbelin, Lewis M. Brown, Vilas Menon, Dritan Agalliu, Irene Munk Pedersen   +16 more
wiley   +1 more source

Fundamentals of Thermal Transport and Energy Conversion in Ultra‐High Temperature Ceramics: From Microscale Mechanisms to Macroscopic Properties

Advanced Science, EarlyView.
This review critically examines thermal transport and radiative properties of ultra‐high temperature ceramics for hypersonic flight, advanced nuclear systems, and next‐generation energy conversion devices. It explores phonon–photon–electron interactions, microstructural engineering, thermoelectric conversion, and machine learning‐accelerated multiscale
Zhipeng Pei, Yue Li, Jiayu Xing, Yue Zhu, Ru Zhang, Huan Wu, Zihao Qin, Gang Pei, Man Li   +8 more
wiley   +1 more source

Throughput quantitative analysis of EDCA 802.11e in different scenarios

Journal of Computer Science and Technology, 2013
This document presents a quantitative analysis of the direct and relative throughput of IEEE 802.11e. The global throughput of an 802.11e WLAN is determined by EDCA (Enhanced Distributed Channel Access) parameters, among other aspects, that are usually ...
Santiago Cristobal Perez, Higinio Alberto Facchini, Gustavo Mercado, Luis Bisaro, Javier Campos   +4 more
doaj  

Design, synthesis, antimicrobial evaluation, and molecular docking studies of novel biphenyl-bearing pyrazole derivatives

Discover Chemistry
In this work, a novel series of biphenyl-based pyrazole compounds (4a–4g) was successfully prepared and their structures were confirmed using standard spectroscopic methods like FT-IR, 1H NMR, 13C NMR, and HRMS.
Dinkal V. Kasundra, Paresh N. Patel
doaj   +1 more source

CD31+ Cell Enrichment Enhances Therapeutic Effects of Stromal Vascular Fraction in Experimental Primary Osteoarthritis: A Preclinical Study in the Dunkin Hartley Guinea Pig Model

Advanced Science, EarlyView.
Both SVF and CD31+ SVF improve spontaneous osteoarthritis, but CD31+ enrichment refines the therapeutic profile rather than broadly enhancing all effects. More distinct benefits are observed in extracellular matrix remodeling, osteochondral integrity, and subchondral/trabecular bone preservation, supporting CD31+‐enriched SVF as a biologically enhanced
Sijia Zhou, Tobias Winkler, Bin Chen, Marta Grzeski, Yilong Yang, Florian N. Fleckenstein, Dominik Geisel, Alexander Hildebrandt, Daniela Aschenbrenner, Marie Agatha Mohn, Benjamin Claass, January Weiner 3rd, Sven Geissler, Georg N. Duda, Søren P. Sheikh, Oliver Klein, Tazio Maleitzke   +16 more
wiley   +1 more source

Enhanced Mechanical Properties Via Boron‐Induced Multi‐Mechanism Strengthening in (NbTaTi1.5V)100‐xBx Refractory High Entropy Alloys

Advanced Science, EarlyView.
A trace amount of boron is introduced into NbTaTi1.5V RHEA, forming a finegrained BCC+TiO+TiB microstructure. The TiB phase generates numerous dislocations, strengthening the alloy. The alloy exhibits 3610 MPa compressive fracture strength and 1060 HV microhardness, while retaining 14.8% fracture strain.
Da Wu, Bo Li, Yuzhi Shi, Cong Li, Eryong Liu, Xiaohu Hou, Yimin Gao, Tao Wu, Pucun Bai, Chenyu Liang   +9 more
wiley   +1 more source

Carbon‐Confined Fe3C/Fe3N Janus Interfaces for Selective Nitric Oxide‐to‐Ammonia Electroreduction

Angewandte Chemie, EarlyView.
A defect‐rich, graphitic‐carbon‐confined Fe3C/Fe3N Janus catalyst integrates NO transport, adsorption/activation, and interfacial H supply for efficient nitric oxide electroreduction to ammonia. Built from earth‐abundant elements, this architecture enables high‐yield and high‐efficiency NH3 synthesis while valorizing industrial NO emissions.
Jialing Song, Ziqi Wei, Haotian Huang, Lupeng Han, Biyi Huang, Evangelina Pensa, Sam Fong Yau Li, Eslam Hamed, Fun Man Fung, Emiliano Cortés, Dengsong Zhang   +10 more
wiley   +2 more sources

Multi‐Omics Profiling of High‐Grade Serous Ovarian Cancer Reveals an Inflammation‐Related Lipid Metabolism Subtype Associated With Platinum Resistance

Advanced Science, EarlyView.
Through integrated proteomic and metabolomic profiling, Zhao et al. identified three molecular subtypes of high‐grade serous ovarian cancer. The high‐risk subtype exhibits activated arachidonic acid metabolism and cyclooxygenase‐2 overexpression. This metabolic axis promotes M2‐like macrophage infiltration, which contributes to platinum resistance ...
Yuxi Zhao, Junyi Li, Bo Zheng, Wanshan Liu, Yaru Wang, Shufeng Wang, Ying Cui, Huiqin Guo, Hongxia Wang, Ting Xiao, Kun Qian, Jing Zuo   +11 more
wiley   +1 more source

Generation of the Camptothecin Scaffold by a Flavin‐Catalyzed Photooxidative Skeletal Reorganization

Angewandte Chemie, EarlyView.
The biosynthetic pathway of the anticancer drug precursor camptothecin involves an enigmatic skeletal reorganization from a 6/5/6 tetrahydro‐β‐carboline to a 6/6/5 pyrroloquinoline ring system. Here, we show that this transformation can be achieved by photooxidation with flavin cofactors, such as flavin mononucleotide (FMN) as catalysts.
Shenyu Liu, Zeliang Zhang, Benedikt Seligmann, Van Hung Bui, Tuan‐Anh Minh Nguyen, Thu‐Thuy T. Dang, Jakob Franke   +6 more
wiley   +2 more sources