Results 71 to 80 of about 780,386 (338)
Distinct EMT programs control normal mammary stem cells and tumour-initiating cells [PDF]
Tumour-initiating cells (TICs) are responsible for metastatic dissemination and clinical relapse in a variety of cancers. Analogies between TICs and normal tissue stem cells have led to the proposal that activation of the normal stem-cell program within ...
Kaygusuz, Yasemin+6 more
core +1 more source
Contactless Tracking of Decomposition in Self‐Reporting Ceramic Cr‐Al‐B Coatings
Proof of concept for contactless tracking of decomposition in self‐reporting ceramic Cr‐Al‐B coatings in extreme environments by contactless resistivity measurements is demonstrated. To verify the results, high resolution in situ and ex situ methods are employed.
Peter J. Pöllmann+13 more
wiley +1 more source
Advancing Power System Services With Privacy-Preserving Federated Learning Techniques: A Review
Digitalization has enabled the potential for artificial intelligence techniques to lead the power system to a sustainable transition by extracting the data generated by widely deployed edge devices, including advanced sensing and metering.
Ran Zheng+3 more
doaj +1 more source
Craniofacial disorders in the course of Tourette’s syndrome - a review of the literature
INTRODUCTION: Tourette's syndrome is a neurological disorder in which the patient presents first symptoms, such as motor and voice tics, in childhood. If the disease significantly impairs proper functioning in society, symptomatic treatment is applied ...
Paulina Ratajska+2 more
doaj +1 more source
The surface chemistry and core composition of Ti3C2Tx MXenes is often derived from X‐ray Photoelectron Spectroscopy (XPS) but its determination and quantification remain difficult due to adsorbed species such as adventitious carbon. This challenge is overcome by using energy‐dependent XPS and depth profile modeling of the Ti3C2Tx MXene surface ...
Zoé Dessoliers+7 more
wiley +1 more source
Physics-Informed Neural Networks for Power Systems Warm-Start Optimization
Several studies have demonstrated the potential of machine learning methods to solve optimal power flow problems. However, designing a scalable physics-informed neural network (PINN) model that can improve its performance being trained in diverse ...
Alex Tudoras-Miravet+3 more
doaj +1 more source
Exclusão digital e políticas públicas de inclusão tecnológica no Estado de São Paulo e capital
O conceito de exclusão digital compreende as extensas camadas das sociedades que ficam à margem do fenômeno da sociedade da informação e da expansão das redes digitais modernas.
Luciano Antonio Rodrigues+1 more
doaj
The CRL7FBXW8 Complex Controls the Mammary Stem Cell Compartment through Regulation of NUMB Levels
In breast cancer (BC), NUMB loss of function (LOF) is common and mainly driven by protein hyper‐degradation. The CRL7FBXW8 complex is the E3 ligase responsible for NUMB degradation. Inhibition of CRL7FBXW8 in NUMB‐LOF BC cells restores NUMB levels, and decreases the number of cancer stem cells and tumorigenic ability in vivo. Targeting CRL7FBXW8 offers
Simone Sabbioni+16 more
wiley +1 more source
This study introduces an integrated analytical and bioinformatics platform for high‐throughput tracing of lipid metabolism using bioorthogonal alkyne fatty acids and optimized LC‐MS workflow. Applied to human fibrosarcoma cells, the method traced fatty acid metabolism, revealing nuances in sphingolipid routing and metabolic bottlenecks, highlighting ...
Palina Nepachalovich+7 more
wiley +2 more sources