Results 81 to 90 of about 780,386 (338)

Clinical effectiveness and patient perspectives of different treatment strategies for tics in children and adolescents with Tourette syndrome: a systematic review and qualitative analysis

open access: yesHealth Technology Assessment, 2016
Background: Tourette syndrome (TS) is a neurodevelopmental condition characterised by chronic motor and vocal tics affecting up to 1% of school-age children and young people and is associated with significant distress and psychosocial impairment ...
Chris Hollis   +18 more
doaj   +1 more source

A Review of the Neuropsychological Dimensions of Tourette Syndrome

open access: yesBrain Sciences, 2017
Neurocognitive functioning in Tourette syndrome (TS) has been the subject of intensive research in the past 30 years. A variety of impairments, presumably related to frontal and frontostriatal dysfunctions, have been observed.
Simon Morand-Beaulieu   +5 more
doaj   +1 more source

Pilot Open Case Series of Voice over Internet Protocol-Delivered Assessment and Behavior Therapy for Chronic Tic Disorders [PDF]

open access: yes, 2016
Comprehensive Behavioral Intervention for Tics (CBIT) is an efficacious treatment for children with chronic tic disorders (CTDs). Nevertheless, many families of children with CTDs are unable to access CBIT due to a lack of adequately trained treatment ...
Bauer, Christopher C.   +4 more
core   +1 more source

Endothelial cells do not arise from tumor-initiating cells in human hepatocellular carcinoma [PDF]

open access: yes, 2013
BACKGROUND: Conventional models of carcinogenesis suggest that tumors recruit blood vessel formation from normal host tissues. This concept has recently been challenged by prominent studies of glioblastoma, which suggest that intratumoral endothelial ...
Anand Ghanekar   +3 more
core   +1 more source

Twin Toughening‐Driven Martensitic Transformation Strategy Synergistic Improvement for Plasticity‐Thermal Shock Resistance of (Hf─Zr─Ti)C Ceramic Coating in Severe Thermal Environments

open access: yesAdvanced Science, EarlyView.
A “ceramic self‐toughening strategy” is introduced for enhancing the plasticity and thermal shock resistance of (Hf─Zr─Ti)C coatings through twin toughening‐driven martensitic transformations in oxide scales. It facilitated the formation of stable, dense, and high‐toughness oxide scales after repeat ablation, and endowed prepared coatings with superior
Jiachen Li   +10 more
wiley   +1 more source

2D/2D MOF/MXene Schottky Junction: Prolonged Carrier Lifetime and Enhanced Hydrogen Evolution Efficiency

open access: yesAngewandte Chemie, EarlyView.
This study designs an innovative 2D/2D Schottky heterojunction by integrating a 2D MOF with exfoliated Ti3C2 MXene. The MXene serves as a hole‐accumulation center, effectively enhancing charge carrier separation, prolonging carrier lifetimes, and achieving an impressive hydrogen evolution rate of 5000 µmol gcat−1 under visible‐light irradiation ...
María Cabrero‐Antonino   +11 more
wiley   +2 more sources

Uso de las herramientas comunicativas en los entornos virtuales de aprendizaje

open access: yesChasqui, 2019
El interés del presente artículo fue analizar el uso de las herramientas comunicativas síncronas y asíncronas en los entornos virtuales de aprendizaje.  Se precisaron autores como, García (2007), Cabero & Llorente (2007), Martínez, F. & Solano, I. (2003),
Hender Alexander Viloria Matheus   +1 more
doaj   +1 more source

Targeted Intervention Strategies for Maternal–Offspring Transmission of Christensenellaceae in Pigs via a Deep Learning Model

open access: yesAdvanced Science, EarlyView.
This study deciphers maternal‐driven microbial transmission in pigs using a deep learning model (maternal–offspring microbial transmission model), identifying Christensenellaceae R‐7 group as a key transmitted taxon. Filtered galacto‐oligosaccharides‐targeted Christensenellaceae R‐7 group alters offspring microbial functions via maternal ...
Haibo Shen   +9 more
wiley   +1 more source

Antiparallel β‐Sheet as a Key Motif of Amyloid‐β Inhibitor Designed via Topological Peptide Reprogramming

open access: yesAngewandte Chemie, EarlyView.
Targeting Amyloid‐β (Aβ) aggregation requires a peptide‐based approach that accounts for the structural heterogeneity of Aβ. Here, we employ topological reprogramming via disulfide bonds to stabilize antiparallel β‐sheets within the dimeric peptide.
Dongjoon Im   +5 more
wiley   +2 more sources

Ocular Tics and Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections (PANDAS)

open access: yesDiseases
Little is known about ocular tics in Pediatric Autoimmune Neuropsychiatric Disorders associated with Streptococcal infections (PANDAS). In this retrospective study, we examined the clinical records of children with motor tics referred to the ...
Stefano Dore   +7 more
doaj   +1 more source

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