Results 51 to 60 of about 5,072 (192)

The intensity distribution among well-trained and elite endurance athletes

open access: yesFrontiers in Physiology, 2015
Researchers have retrospectively analyzed the training intensity distribution (TID) of nationally and internationally competitive athletes in different endurance disciplines to determine the optimal volume and intensity for maximal adaptation.
Thomas Leonhard Stöggl, Billy eSperlich
doaj   +1 more source

Effects of total ionizing dose on transient ionizing radiation upset sensitivity of 40–180 nm SRAMs

open access: yesAIP Advances, 2022
Effects of total ionizing dose (TID) on the transient radiation upset sensitivity of commercial static random access memories (SRAMs) were investigated.
Junlin Li   +8 more
doaj   +1 more source

Genomic Insights Into Risperidone Treatment Outcomes in Children and Adolescents: Experience From a Psychiatric Hospital Serving Rural Youth

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Risperidone is a commonly used antipsychotic for treating psychiatric illness in children and adolescents. There is a large variability in risperidone response and discontinuation rates remain high. Pharmacogenomics offers the opportunity to improve risperidone outcomes, yet studies in pediatric populations are limited.
Jack W. Staples   +10 more
wiley   +1 more source

Simulation of Total Ionizing Dose (TID) Effects Mitigation Technique for 22 nm Fully-Depleted Silicon-on-Insulator (FDSOI) Transistor

open access: yesIEEE Access, 2020
Based on 22 nm ultrathin-body fully depleted silicon-on-insulator (UTB-FDSOI) transistors, we propose a novel structure of buried insulator layer aiming at total ionizing dose (TID) effects mitigation. Using technology computer-aided design (TCAD) tools,
Gangping Yan   +6 more
doaj   +1 more source

Clinical Model‐Informed Precision Dosing Consult Service for Accelerating Personalized Medication in Pediatric Patients

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Traditional dosing strategies often rely on a “one‐size‐fits‐all” paradigm, assuming an “average” patient with typical demographic and pharmacological characteristics. In reality, this often overlooks existing between‐patient variability and can lead to suboptimal drug exposure or toxicity. This issue is especially pronounced in pediatric patients, who
Zachary L. Taylor   +12 more
wiley   +1 more source

Do Brain Extracellular Fluid Concentrations Predict PET‐Inferred Receptor Occupancy in Human CNS? A Mechanistic Model‐Based Analysis of Dopamine D2 Receptor Ligands

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
A mechanistic CNS PBPK model framework was applied to eight antipsychotic D2 receptor ligands, comparing brain extracellular fluid (brainECF) and brain cell membrane (brainM) as biophase for predicting human receptor occupancy compared against PET neuroimaging data. BrainM concentrations showed improved agreement with PET‐derived receptor occupancy for
Divakar Budda   +2 more
wiley   +1 more source

Transient ischemic dilation as a diagnostic marker in myocardial perfusion SPECT protocols: a systematic review and meta-analysis

open access: yesMajalah Kardiologi Indonesia, 2020
Background: Transient ischemic dilation (TID) measures left ventricle (LV) volume changes which can be associated with combination of myocardial and endocardial ischemia.
Nasim Namiranian   +3 more
doaj   +1 more source

Syllables in TİD

open access: yesDilbilim Araştırmaları Dergisi, 2018
We have two aims in this paper. Our first aim is to show that syllables exist in TİD prosody (Türk İşaret Dili – Turkish Sign Language). A specific domain in prosody is substantiated only if there are phonological phenomena that refer to that domain as part of their definition.
openaire   +4 more sources

Corticocortical evoked potential amplitude is altered by cortical stimulation in epilepsy

open access: yesEpilepsia, EarlyView.
Abstract Objective Neurostimulation is an established therapy for drug‐resistant epilepsy, but optimizing stimulation parameters remains a major challenge. Corticocortical evoked potential (CCEP) amplitude may serve as an immediate biomarker of neurostimulation effects, enabling rapid parameter optimization.
Bethany J. Stieve   +4 more
wiley   +1 more source

Inkluderingens banor

open access: yesSociologisk Forskning
I denna studie undersöks hur skyddssökande som kom till Sverige 2014-2015 orienteras i en ny tillvaro och hur deras orientering och meningsskapande ändras över tid. Utifrån en longitudinell design där vi intervjuat deltagarna vid två tillfällen med några
Magnus Dahlstedt   +2 more
doaj   +1 more source

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