Results 31 to 40 of about 2,639 (222)

Nucleoside‐Modified mRNA Encoding Alpha‐Galactosidase A Ameliorates Fabry Disease Phenotypes in Human IPSC‐Derived Cardiomyocytes

Advanced Science, EarlyView.
Human iPSC‐derived Fabry cardiomyocytes exhibited broad transcriptional dysregulation, apoptosis, mitochondrial dysfunction, impaired reactive oxygen species handling, altered contractility, and abnormal calcium transient decay, potentially mediated by phospholamban hyperphosphorylation.
Malte Juchem, Lea Oehlsen, Sedef Ersoy, Jia Li Ye, Natalie Weber, Elisa Mohr, Wilson Agyapong, Junqing Liu, Maximilian Fuchs, Ke Xiao, Christopher Jahn, Reto Eggenschwiler, Tobias Cantz, Julia Beimdiek, Falk F. R. Buettner, Theresia Kraft, Jan Hegermann, Ivonne J. Knorr, Lisa Ernst, Linda Feldbrügge, Resa Puffert, Kevin Schmidt, Christian Bär, Jeannine Hoepfner, Thomas Thum   +24 more
wiley   +1 more source

A numerical study of tidal bores

Journal of Physics: Conference Series, 2019
Abstract A tidal bore is a natural phenomenon forming a positive surge upstream and it has a remarkable effect on estuary zones and river ecologies. The tidal bore formation controlled by channel properties, tidal characteristics, and river discharge remains a research challenge.
N S Ningsih, N L Siddiq, A Tarya
openaire   +1 more source

SPH modeling of tidal bore scenarios [PDF]

Natural Hazards, 2014
The paper presented a smoothed particle hydrodynamics (SPH) method to study the three-dimensional (3D) tidal bore scenarios. The SPH method is a mesh-free particle modeling technique that can track the large deformation of free surfaces in a straightforward and accurate way.
Liu, H., Li, J., Shao, S., Tan, S.K.
openaire   +2 more sources

Participatory Policy Development: Reflections on Designing the Strong Roots for Our Futures Program in Victoria

Australian Journal of Social Issues, EarlyView.
ABSTRACT In this paper, we trace the journey to create the Strong Roots for our Futures Program, a government program to resource and support Traditional Owners to undertake a range of activities in areas where no state recognition existed. We provide a background to state recognition in Victoria before considering the program design, leading to an ...
Nell Reidy, Bhiamie Williamson, Jesse Williams   +2 more
wiley   +1 more source

Environmental Effect of Tidal Bore Propagation in Kampar River

MATEC Web of Conferences, 2017
The environmental effect of the tidal bore propagation in kampar river is investigated. Propagation of the tidal bore satisfy Korteweg and de Vries (KdV) equation where the environmental effect will be given as a perturbation term of the KdV equation ...
Mubarak, Sulaiman Albertus, Efriyeldi
doaj   +1 more source

Scanning Parametric Sediment Echosounder as Tool for Underwater Archaeological Prospection

Archaeological Prospection, EarlyView.
ABSTRACT Underwater cultural heritage 3D prospection techniques, especially for remains that are partly buried in the ground, are only very rarely available and often can only be applied with considerable technical effort. To overcome this limitation, we evaluate a methodological adaption of widely used and available single channel parametric sediment ...
Dennis Wilken, Philipp Held, Jacob Geersen, Marcel Bradtmöller, Peter Feldens, Jens Schneider v. Deimling   +5 more
wiley   +1 more source

Biochar‐based fertilizers improve nutrient use efficiency in sunflower grown on a subtropical tidal soil

Biofuels, Bioproducts and Biorefining, EarlyView.
Abstract Improving fertilizer use efficiency is essential for reducing environmental pollution, sustaining agricultural production, and maximizing the economic profitability of crop production systems. This study tested the hypothesis that the formulation strategy of biochar‐based fertilizers, rather than nutrient addition alone, is associated with ...
Md. Al‐Amin, Miftahul Jannat Mim, S. M. Mahbubul Alam, Shamim Mia, M. M. Masud, Gopal Saha, Md. Abdul Kader, Keiji Jindo   +7 more
wiley   +1 more source

Listening to young children with disabilities: Experiences of quality in mainstream primary education

British Educational Research Journal, EarlyView.
Abstract All children should have access to quality education through a child‐centred pedagogy. An inclusive, child‐centred pedagogy uses a strength‐based view of children that recognises each child as unique and competent, providing children with multiple opportunities to explore and learn at their own pace.
Katherine Gulliver
wiley   +1 more source

Trendelenburg positioning with or without norepinephrine infusion for haemodynamic support in anaesthetised hypovolemic horses

Equine Veterinary Journal, EarlyView.
Abstract Background Intraoperative haemorrhage during equine anaesthesia is a rare but potentially fatal complication requiring prompt haemodynamic support. Postural manoeuvres such as Trendelenburg (TL) positioning and vasopressor support augment venous return and improve cardiac output (CO), yet their efficacy in anaesthetised hypovolemic horses ...
Vaidehi V. Paranjape, Klaus Hopster, Ismar Lutvikadic, Bernd Driessen   +3 more
wiley   +1 more source

Hydrodynamic Modelling of Severn Bore and Its Dependence on Ocean Tide and River Discharge

Journal of Marine Science and Engineering
Owing to the high tidal range, the Severn Estuary and Bristol Channel have the potential to generate huge amounts of renewable electricity for the UK. During the flood tide, the surging water travels upstream to form the Severn Bore.
Bowen Che, Hao Hu, Jun Ma, Dongfang Liang   +3 more
doaj   +1 more source