Results 91 to 100 of about 10,927,898 (348)

EEPD1 Inhibition Unleashes Antitumor Immunity in Colorectal Cancer by Activating the cGAS‐STING Pathway

Advanced Science, EarlyView.
In colorectal cancer, high expression of the DNA repair protein EEPD1 correlates with immune exclusion and poor prognosis. This study demonstrates that EEPD1 depletion induces genomic instability, leading to cytosolic DNA accumulation and subsequent activation of the cGAS‐STING‐type I interferon pathway. This cascade remodels the tumor microenvironment
Liyun Huo, Chong Wu, Xiaobo Li, Caina Ma, Jiamin Huang, Zishuo Chen, Weiling He, Tianyu Tao, Weijing Zhang   +8 more
wiley   +1 more source

Power Extraction Strategy of a Robust kW Range Marine Tidal Turbine Based on Permanent Magnet Synchronous Generators and Passive Rectifiers [PDF]

, 2014
This paper presents a kW range marine tidal current power generation system consisting of a fixed pitch marine current turbine (MCT) with two permanent magnet synchronous generators in the turbine shaft, two diode rectifiers (each rectifier is associated
CHARPENTIER, Jean-Frederic, ODEDELE, Nafissah, OLMI, Christophe   +2 more
core   +2 more sources

Review: Insight on Porous Carbon Positive Electrode for Sodium‐Ion Capacitors: Interplay Between Synthesis, Properties, and Performance

Advanced Science, EarlyView.
Sodium ion capacitor (SIC) is currently constrained by the low discharge capacity of commercial activated carbon as positive electrode material. This review provides a holistic summary of research efforts on alternative porous carbon materials for SIC. Image created by the authors with www.biorender.com.
Ademola Adeniji, Adrian Beda, Camélia Matei Ghimbeu   +2 more
wiley   +1 more source

Selective Electrolysis of Water Under Artificial Seawater Conditions Using Transition Metal Borate Anodes

Advanced Energy Materials, EarlyView.
The borate‐based cobalt‐iron catalyst promotes selective oxidation of water rather than chlorine evolution reaction during electrolysis of seawater. When integrated into a zero‐gap electrolyzer prototype, this catalyst supports robust splitting of artificial seawater into oxygen and hydrogen on an extended timescale.
Ananta R. Fareza, Hank Garg, Luis Miguel Azofra, Darcy Simondson, Tam D. Nguyen, Mohamed R. Rizk, Khang N. Dinh, Rosalie K. Hocking, Douglas R. MacFarlane, Hoang‐Long Du, Alexandr N. Simonov   +10 more
wiley   +1 more source

Maximum Torque Per Ampere Control Strategy of a 5-phase PM Generator in healthy and faulty modes for tidal marine turbine application [PDF]

, 2014
The work presented in this paper aims to propose a control strategy being able to extract efficiently energy from a fixed-pitch marine current turbine associated with a 5–phase Permanent Magnet Synchronous Generator (PMSG) in healthy mode and in faulty ...
CHARPENTIER, Jean-Frederic, FALL, Ousmane, LETELLIER, Paul, NGUYEN, Ngac Ky   +3 more
core   +4 more sources

Seasonal variation of the three-dimensional mean circulation over the Scotian Shelf [PDF]

, 1997
The seasonal-mean circulation over the Scotian Shelf is studied numerically by computing mean and tidal current fields for winter, spring, and summer using a three-dimensional nonlinear diagnostic model.
Han, Guoqi, Hannah, Charles G., Loder, John W., Smith, Peter C.   +3 more
core   +1 more source

Laparoscopic Colorectal Surgery in the Era of Robotics: Evolution, Eclipse, or Equilibrium?

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Minimally invasive colorectal surgery has undergone a remarkable transformation over the past three decades. Laparoscopy, once viewed with skepticism, is now firmly established as a standard approach, supported by robust randomized trials demonstrating oncologic safety and improved recovery compared to open surgery.
Amanjeet Singh, Archit Gupta, Azhar Perwaiz, Adarsh Chaudhary   +3 more
wiley   +1 more source

Health disparities in chronic liver disease

Hepatology, EarlyView., 2022
Abstract The syndemic of hazardous alcohol consumption, opioid use, and obesity has led to important changes in liver disease epidemiology that have exacerbated health disparities. Health disparities occur when plausibly avoidable health differences are experienced by socially disadvantaged populations.
Ani Kardashian, Marina Serper, Norah Terrault, Lauren D. Nephew   +3 more
wiley   +1 more source

Rethinking Perioperative Corticosteroids in Esophageal Cancer Surgery: Evidence From an Integrative Meta‐Analysis

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Background Esophagectomy remains a highly invasive procedure associated with substantial postoperative morbidity. Pulmonary complications, anastomotic leakage, and in‐hospital mortality are of particular concern. Perioperative corticosteroids are often administered to attenuate excessive inflammatory responses; however, the clinical impact in ...
Tomohiko Yasuda, Akihisa Matsuda, Nobutoshi Hagiwara, Yoshiharu Nakamura, Hiroshi Yoshida   +4 more
wiley   +1 more source

Enhanced bottom-ice algal biomass across a tidal strait in the Kitikmeot Sea of the Canadian Arctic

Elementa: Science of the Anthropocene, 2019
Sea ice algae are an important contributor of primary production in the Arctic ecosystem. Within the bottom-ice environment, access to nutrients from the underlying ocean is a major factor controlling production, phenology, and taxonomic composition of ...
Laura A. Dalman, Brent G.T. Else, David Barber, Eddy Carmack, William J. Williams, Karley Campbell, Patrick J. Duke, Sergei Kirillov, Christopher J. Mundy   +8 more
doaj   +1 more source