ABSTRACT Small cell lung cancer (SCLC) is a highly aggressive neuroendocrine malignancy with an immunosuppressive tumor microenvironment, and current immunotherapy provides limited benefit. This highlights the need to identify microenvironmental features enabling effective immune responses.
Jiatian Fang +4 more
wiley +1 more source
Development and validation of a cuproptosis-related lncRNA signature for predicting prognosis and immunotherapy response in breast cancer: a retrospective analysis of TCGA data. [PDF]
Hu P +5 more
europepmc +1 more source
The rising tide: Trends in induction of labor at term over a 5‐year period at a single centre
Abstract Objective Induction of labor (IOL) is a controversial topic in contemporary obstetric practice, with some suggesting that the increase in elective induction (eIOL) as a potential contributor to increasing cesarean delivery (CD) rates. The objectives of this single‐center study were to examine the rates of IOL, trends in indications for IOL ...
Sarah M. Nicholson +7 more
wiley +1 more source
Improved closure of the global mean sea level budget from observational advances since 1960. [PDF]
Zheng H +7 more
europepmc +1 more source
A compendium of extracellular vesicle biogenesis inhibitors: From bench to bedside
This review explores a decade of research on extracellular vesicles (EVs), detailing their biogenesis and roles in health and disease. It emphasizes EVs' relevance for potential medical applications covering various conditions such as cancer, neurodegeneration, inflammation, and infectious diseases, bridging experimental findings with clinical ...
Stefano Vecchione +2 more
wiley +1 more source
PFAS from a Discrete-Event Terrestrial Source Migrates with Groundwater to Intertidal Seepages. [PDF]
Briggs MA +8 more
europepmc +1 more source
Visual Patterns of Diaphragmatic Motion in Acute Respiratory Failure: A Prospective Pilot Study
In this prospective bicentric study, we studied the relationship between the appearance of diaphragmatic motion and the etiological diagnosis of patients admitted to the emergency department with ARF. We observed a different visual pattern in patients with pneumonia. This is an interesting result as it allows the diagnosis of pneumonia without the need
Thibaut Markarian +7 more
wiley +1 more source
Assessing the temporal clustering of coastal storm tide hazards under natural variability in a near 500-year model run. [PDF]
Jenkins LJ +6 more
europepmc +1 more source

