Results 41 to 50 of about 1,578 (244)

Investigation of Acoustic Waves in the Ionosphere Generated by a Deep Convection System Using Distributed Networks of GPS Receivers and Numerical Modeling

Geophysical Research Letters, 2018
Acoustic waves generated in the lower atmosphere may become an important source of variability in the upper atmosphere. Although excited with small amplitudes compared to gravity waves, they are minimally subjected to viscous dissipation and may reach ...
Irfan Azeem, Richard L. Walterscheid, Geoff Crowley   +2 more
doaj   +1 more source

Subperiosteal circumferential connective tissue graft for vertical implant soft tissue augmentation

Clinical Advances in Periodontics, EarlyView.
Abstract Background Vertical implant soft tissue augmentation is indicated to optimize esthetic outcomes in cases of peri‐implant soft tissue deficiency or dehiscence, particularly when the peri‐implant mucosa is exposed during a full smile. This manuscript describes the use of a subperiosteal circumferential connective tissue graft (SC CTG) for ...
Jonathan H. Do, Alex S. Kim
wiley   +1 more source

Three‐Dimensional Reconstruction of Ionospheric Disturbances Using Tikhonov Regularization After 2022 Tonga Volcanic Eruption

Earth and Space Science
Following significant natural hazards, traveling ionospheric disturbances (TIDs) are generated that affect the ionosphere. Understanding the three‐dimensional structure of these TIDs is crucial for understanding their propagation mechanisms.
Danial Abdollahi, M. Mahdi Alizadeh, Harald Schuh, Lung‐Chih Tsai   +3 more
doaj   +1 more source

Genomic Insights Into Risperidone Treatment Outcomes in Children and Adolescents: Experience From a Psychiatric Hospital Serving Rural Youth

Clinical Pharmacology &Therapeutics, EarlyView.
Risperidone is a commonly used antipsychotic for treating psychiatric illness in children and adolescents. There is a large variability in risperidone response and discontinuation rates remain high. Pharmacogenomics offers the opportunity to improve risperidone outcomes, yet studies in pediatric populations are limited.
Jack W. Staples, Shayna R. Killam, Karen E. Brown, Rachel Dalton, Elizabeth Sather, Qiang Chen, Joshua Loveland, Corbin Schwanke, Abdallah F. Elias, Kristin L. Bigos, Erica L. Woodahl   +10 more
wiley   +1 more source

Some aspects of large-scale travelling ionospheric disturbances which originate at conjugate locations in auroral zones, cross the equator and sometimes encircle the earth [PDF]

Annales Geophysicae, 2011
The occurrence of large-scale travelling ionospheric disturbances (LS-TIDs) has been examined. Initially some literature on their generation is considered.
G. G. Bowman, I. K. Mortimer
doaj   +1 more source

Clinical Model‐Informed Precision Dosing Consult Service for Accelerating Personalized Medication in Pediatric Patients

Clinical Pharmacology &Therapeutics, EarlyView.
Traditional dosing strategies often rely on a “one‐size‐fits‐all” paradigm, assuming an “average” patient with typical demographic and pharmacological characteristics. In reality, this often overlooks existing between‐patient variability and can lead to suboptimal drug exposure or toxicity. This issue is especially pronounced in pediatric patients, who
Zachary L. Taylor, Takanobu Nadai, Kei Irie, Wen Rui Tan, Sanjana Parikh, Anhar Hosawi, Matthijs W. van Hoogdalem, Ronaldo Morales Junior, Sonya Tang Girdwood, Abbie D. Leino, Kana Mizuno, Alexander A. Vinks, Tomoyuki Mizuno   +12 more
wiley   +1 more source

Do Brain Extracellular Fluid Concentrations Predict PET‐Inferred Receptor Occupancy in Human CNS? A Mechanistic Model‐Based Analysis of Dopamine D2 Receptor Ligands

Clinical Pharmacology &Therapeutics, EarlyView.
A mechanistic CNS PBPK model framework was applied to eight antipsychotic D2 receptor ligands, comparing brain extracellular fluid (brainECF) and brain cell membrane (brainM) as biophase for predicting human receptor occupancy compared against PET neuroimaging data. BrainM concentrations showed improved agreement with PET‐derived receptor occupancy for
Divakar Budda, J.G. Coen van Hasselt, Elizabeth C.M. de Lange   +2 more
wiley   +1 more source

Observations of ionospheric disturbances associated with the 2020 Beirut explosion by Defense Meteorological Satellite Program and ground-based ionosondes [PDF]

Annales Geophysicae
A major explosion that released a significant amount of energy into the atmosphere occurred in Beirut on 4 August 2020. The energy released may have reached the upper atmosphere and generated some traveling ionospheric disturbances (TIDs), which can ...
R. Pradipta, P.-C. Lai
doaj   +1 more source

Progress report on new epilepsy treatments: A summary of the Eighteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XVIII). II. Treatments in more advanced clinical development

Epilepsia, EarlyView.
Abstract This article summarizes data for 13 investigational treatments for which at least preliminary seizure outcome data in patients with epilepsy were reported at the Eighteenth Eilat Conference on New Antiepileptic Drugs and Devices held in Madrid, Spain, on May 3–6, 2026.
Meir Bialer, Cecilie Johannessen Landmark, Matthias J. Koepp, Emilio Perucca, Piero Perucca, Torbjörn Tomson, H. Steve White, Elaine Wirrell   +7 more
wiley   +1 more source

Progress report on new epilepsy treatments: A summary of the Eighteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XVIII). I. Treatments in preclinical and early clinical development

Epilepsia, EarlyView.
Abstract Over the last 34 years, the Eilat Conference on New Antiepileptic Drugs and Devices has provided an interactive forum for stakeholders to discuss investigational and recently licensed treatments for seizures and epilepsy. The Eighteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XVIII) took place in Madrid, Spain, on May 3 ...
Meir Bialer, Cecilie Johannessen Landmark, Matthias J. Koepp, Emilio Perucca, Piero Perucca, Torbjörn Tomson, H. Steve White, Elaine Wirrell   +7 more
wiley   +1 more source