Results 11 to 20 of about 948 (171)

AN ALTERNATIVE MODEL FOR TEACHING TENDON REPAIR AND SURGICAL TECHNIQUE IN HAND SURGERY [PDF]

open access: yesActa Ortopédica Brasileira, 2022
Introduction At the beginning of the medical career, the orthopedic surgeon in academic training needs valid methodologies for training complex surgeries in tissues that simulate real situations.
Vinicius Costa Patto dos Santos   +5 more
doaj   +2 more sources

Matrix WaveTM System for Mandibulo-Maxillary Fixation—Just Another Variation on the MMF Theme?—Part II: In Context to Self-Made Hybrid Erich Arch Bars and Commercial Hybrid MMF Systems—Literature Review and Analysis of Design Features [PDF]

open access: yesCraniomaxillofacial Trauma & Reconstruction
Study design: Trends in the utilization of Mandibulo-Maxillary Fixation (MMF) are shifting nowadays from tooth-borne devices over specialized screws to hybrid MMF devices.
Carl-Peter Cornelius   +9 more
doaj   +2 more sources

La relación de las tarabitas, horquetas o ganchos de atalaje con el tráfico de bienes en momentos tardíos prehispánicos

open access: yesEstudios Atacameños, 2007
Se presenta una actualización de la problemática sobre tarabitas, horquetas o ganchos de atalaje, los que fueron utilizados para atar los bultos a las llamas cargueras y para ajusfar los fardos funerarios.
María Gabriela Raviña   +2 more
doaj   +2 more sources

Bioinspired Soft‐Skeleton Robotics With Cooperative Shape Transformation and Stiffness Adaptation

open access: yesAdvanced Robotics Research, EarlyView.
A bioinspired soft‐skeleton robot that integrates variable‐stiffness chain skeletons into a soft textile skin is developed. The chain skeletons are highly flexible initially but can stiffen upon pneumatic actuation, enabling large deformation and enhanced load‐bearing capacity.
Mengyuan Niu   +5 more
wiley   +1 more source

ZDHHC9‐Mediated Palmitoylation of ACSL4 Drives Ferroptosis in Diabetes Mellitus–Induced Erectile Dysfunction

open access: yesAdvanced Science, EarlyView.
ABSTRACT Diabetes mellitus‐induced erectile dysfunction (DMED) is a highly prevalent complication among diabetic patients; however, its underlying pathogenic mechanisms remain incompletely understood. Metabolic disorder is a hallmark of diabetes, yet its precise contribution to DMED progression is not well defined.
Wanyang Guo   +14 more
wiley   +1 more source

Covalent Inhibition of SHMT2 by Gambogic Acid Induces Ferroptosis Through Mitochondrial Collapse in Triple‐Negative Breast Cancer

open access: yesAdvanced Science, EarlyView.
In this study, chemoproteomics combined with genetic and functional analyses was integrated to identify SHMT2 as a covalent and functional target of gambogic acid (GA) in triple‐negative breast cancer (TNBC). Further validation demonstrated that GA selectively modifies the Cys241 site of SHMT2, triggering mitochondrial dysfunction, activating the Nrf2 ...
Tong Yang   +15 more
wiley   +1 more source

Bioorthogonal Fluorogenic Reporters for Noninvasive Imaging and Urinalysis of Immunotherapeutic Response in Renal Cell Carcinoma

open access: yesAdvanced Science, EarlyView.
This study reported renal‐clearable bio‐orthogonal near‐infrared fluorogenic probes (BGRs) that specifically imaging and urinalysis of granzyme B for dynamic evaluation of RCC immunotherapy. BGRs not only differentiate immunotherapeutic responses in orthotopic RCC mice, but also enable sensitive optical urinalysis of granzyme B in clinical specimens ...
Xingyue Yang   +9 more
wiley   +1 more source

Engineering Microbial Particles for Next‐Generation Biomedical Platforms

open access: yesAdvanced Science, EarlyView.
Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li   +7 more
wiley   +1 more source

MIS12 Is Required for Kinetochore‐Microtubule Attachment in Oocyte Meiosis

open access: yesAdvanced Science, EarlyView.
A model depicting the role of MIS12 in K‐MT attachment during oocyte meiosis. The presence of MIS12 stabilizes bipolar K‐MT attachments by maintaining the function of NDC80 and its interaction with TUBB. This, in turn, promotes KNL1 assembly and subsequent SAC protein recruitment to kinetochores.
Jian Li   +9 more
wiley   +1 more source

Longitudinal Single‐Axon‐Resolution Imaging of Peripheral Nerve Injury Response in Mice Using an Optical Window Implant

open access: yesAdvanced Science, EarlyView.
A minimally invasive optical window enables stable, long‐term imaging of peripheral nerves in vivo at single‐axon resolution. Dynamic processes of degeneration, regeneration, and cellular remodeling are visualized across multiple time scales within the same nerve region, providing a unique platform to study a variety of anatomical and molecular events ...
Igor D. Luzhansky   +15 more
wiley   +1 more source

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