Results 71 to 80 of about 30,913 (261)

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

Molecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Some Properties of Relay Fusion Frames in Finite Dimensions

Axioms
In this paper, we analyze the relationship between relay fusion frames and standard fusion frames in finite-dimensional real Hilbert spaces. We propose an optimal design method for tight relay fusion frames in the setting of orthogonal subspaces ...
Jianxia Zhang, Zuhua Guo, Guoqing Hong, Fugen Gao, Xinyan Li   +4 more
doaj   +1 more source

A Note on Block-Sparse Signal Recovery with Coherent Tight Frames

Discrete Dynamics in Nature and Society, 2013
This note discusses the recovery of signals from undersampled data in the situation that such signals are nearly block sparse in terms of an overcomplete and coherent tight frame D. By introducing the notion of block D-restricted isometry property (D-RIP)
Yao Wang, Jianjun Wang, Zongben Xu
doaj   +1 more source

Tight Wavelet Frame Decomposition and Its Application in Image Processing

Journal of Mathematical and Fundamental Sciences, 2013
This paper is devoted to the formulation of a decomposition algorithm using tight wavelet frames, in a multivariate setting. We provide an alternative method for decomposing multivariate functions without accomplishing any tensor product. Furthermore, we
Mahmud Yunus, Hendra Gunawan
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

The Studies of (Dual) Fusion Frames on Hilbert Space and Generalization of the Index Set

Mathematics
In this paper, we begin with the classical concept of tight frames in Hilbert spaces. First, we introduce the orthogonal projection P between H and θ(H) (the range of the frame transform θ associated with a traditional tight frame) and investigate the ...
Fangfang Dong, Ruichang Pei
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source