Results 181 to 190 of about 3,715,768 (201)

Large‐scale Whole‐Exome Sequencing Defines the Protein‐Coding Architecture of Retinal Structure, Visual Function, and Major Blinding Diseases

Advanced Science, EarlyView.
Large‐scale whole‐exome sequencing in 356,982 UK Biobank participants defines the protein‐coding architecture of retinal structure, visual function, and major blinding diseases. Pleiotropic genes, including CFI, C3, and RIOX1, bridge multiple retinal phenotypes, while experimental validation of FYB2 implicates RPE barrier dysfunction, providing ...
Jianqing Li, Yijun Ge, Jingxiao Du, Liu Yang, Bangsheng Wu, Chenyue Hang, Mengxi Shen, Yimin Mao, Ting Zhang, Qiyu Bo, Tianyuan Zhao, Yutian Jiao, Yazhi Wang, Shunxiang Gao, Jieqiong Chen, Junran Sun, Tong Li, Huixun Jia, Yang Dou, Wei Cheng, Xiaoling Wan, Jintai Yu, Xiaodong Sun, Bai Lu   +23 more
wiley   +1 more source

PEAR1 Promotes Glucose Metabolism Reprogramming in Sepsis‐Associated Acute Lung Injury via AARS1‐Mediated HIF‐1α Lactylation

Advanced Science, EarlyView.
This study revealed that a PEAR1/HIF‐1α/ glycolysis/lactate/H3K18la positive feedback loop in PMVECs that drives the development of S‐ALI. Mechanistically, PEAR1 mediates the binding of HIF‐1α to AARS1, leading to the lactylation of HIF‐1α, the primary lactylation site of which is K172.
Shuai Li, Zongqing Lu, Pu Fang, Qingqing Pang, Xianghui Wu, Bo Wang, Min Liang, Jingjing Pan, Haobo Kong, Haijian Cai, Juanjuan Li, Jiaying Kang, Dongsheng Wang, Dunling Xia, Mengmeng Xu, Qinghai You   +15 more
wiley   +1 more source

Hollow Cu2O Nanozymes Enhance Probiotic Therapy for Colitis via Redox Homeostasis and TXNIP/NLRP3 Inflammasome Inhibition

Advanced Science, EarlyView.
Hollow cuprous oxide (H‐Cu2O) nanozymes feature enlarged catalytic surfaces for superior reactive oxygen species (ROS) scavenging. By efficiently neutralizing mucosal ROS, H‐Cu2O directly suppresses the TXNIP/NLRP3 inflammasome axis and restores intestinal epithelial barrier integrity.
Guangzhao Wang, Jialing Cao, Pengfei Li, Yujie Wang, Shiqi Lu, Kangliang Sheng, Shan Gao, Yongzhong Wang   +7 more
wiley   +1 more source

Effect of a tightly focused chirped Gaussian laser pulse on electron acceleration in helical undulator

Physics of Plasmas, 2020
The chirped-pulse inverse free electron laser (CIFEL) interaction has been investigated by considering a tightly focused chirped Gaussian laser pulse and a helical undulator in vacuum.
Moohyun Yoon, Sandeep Kumar, D N Gupta
exaly   +2 more sources

Electromagnetic fields of an ultra-short tightly-focused radially-polarized laser pulse

Optics Communications, 2017
Fully analytic expressions, for the electric and magnetic fields of an ultrashort and tightly focused laser pulse of the radially polarized category, are presented to lowest order of approximation. The fields are derived from scalar and vector potentials,
Jian-Xing Li, Yousef I Salamin
exaly   +2 more sources

Multiple filamentation and supercontinuum emission from tightly focused femtosecond laser pulses in air

, 2007
Filamentation characteristics of tightly focused 45 fs laser pulses in air are investigated using transverse imaging in the power range of 20-200 GW.
Suman Bagchi, P Prem Kiran, G Ravindra Kumar   +2 more
exaly   +2 more sources

Some of the next articles are maybe not open access.

Related searches:

Tightly focused laser scanning excites displacement resonance

2022
Shi-wei Chu, Junichi Takahara, Yu-Lung Tang   +2 more
exaly  

Spatial characteristics of motion and emission from electron driven by linearly polarized tightly focused laser pulses

Optik, 2019
Zuxing Zhang, Kang Li, Youwei Tian
exaly  

Electron acceleration in vacuum induced by a tightly focused chirped laser pulse

Applied Physics Letters, 2010
Jianguo Tian, Jian-Xing Li, Wei-Ping Zang   +2 more
exaly  

Laser-induced breakdown and damage in bulktransparent materials induced by tightly focused femtosecond laserpulses

Measurement Science and Technology, 2001
Chris B. Schaffer, Eric Mazur
exaly