Results 21 to 30 of about 15,131,393 (64)

Review of deep learning: concepts, CNN architectures, challenges, applications, future directions

open access: yesJournal of Big Data, 2021
In the last few years, the deep learning (DL) computing paradigm has been deemed the Gold Standard in the machine learning (ML) community. Moreover, it has gradually become the most widely used computational approach in the field of ML, thus achieving ...
Laith Alzubaidi   +9 more
semanticscholar   +1 more source

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1

open access: yesAutophagy, 2021
In 2008, we published the first set of guidelines for standardizing research in autophagy. Since then, this topic has received increasing attention, and many scientists have entered the field.
D. Klionsky   +499 more
semanticscholar   +1 more source

Tocilizumab in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial

open access: yesThe Lancet, 2021
Summary Background In this study, we aimed to evaluate the effects of tocilizumab in adult patients admitted to hospital with COVID-19 with both hypoxia and systemic inflammation.
O. Abani   +499 more
semanticscholar   +1 more source

Safety and efficacy of an rAd26 and rAd5 vector-based heterologous prime-boost COVID-19 vaccine: an interim analysis of a randomised controlled phase 3 trial in Russia

open access: yesThe Lancet, 2021
Background A heterologous recombinant adenovirus (rAd)-based vaccine, Gam-COVID-Vac (Sputnik V), showed a good safety profile and induced strong humoral and cellular immune responses in participants in phase 1/2 clinical trials.
D. Logunov   +30 more
semanticscholar   +1 more source

Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individuals

open access: yesNature Genetics, 2022
We conduct a genome-wide association study (GWAS) of educational attainment (EA) in a sample of ~3 million individuals and identify 3,952 approximately uncorrelated genome-wide-significant single-nucleotide polymorphisms (SNPs).
A. Okbay   +300 more
semanticscholar   +1 more source

Euclid. I. Overview of the Euclid mission [PDF]

open access: yesAstronomy & Astrophysics
The current standard model of cosmology successfully describes a variety of measurements, but the nature of its main ingredients, dark matter and dark energy, remains unknown.
Euclid Collaboration Y. Mellier   +499 more
semanticscholar   +1 more source

High-precision measurement of the W boson mass with the CDF II detector.

open access: yesScience, 2022
The mass of the W boson, a mediator of the weak force between elementary particles, is tightly constrained by the symmetries of the standard model of particle physics. The Higgs boson was the last missing component of the model.
T. Aaltonen   +396 more
semanticscholar   +1 more source

Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life Years for 29 Cancer Groups From 2010 to 2019

open access: yesJAMA Oncology, 2021
Key Points Question What was the burden of cancer globally and across Sociodemographic Index (SDI) groupings in 2019, and how has incidence, morbidity, and mortality changed since 2010?
Jonathan M Kocarnik   +499 more
semanticscholar   +1 more source

Global burden of bacterial antimicrobial resistance 1990–2021: a systematic analysis with forecasts to 2050

open access: yesThe Lancet
Summary Background Antimicrobial resistance (AMR) poses an important global health challenge in the 21st century. A previous study has quantified the global and regional burden of AMR for 2019, followed with additional publications that provided more ...
M. Naghavi   +499 more
semanticscholar   +1 more source

Global burden and strength of evidence for 88 risk factors in 204 countries and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021

open access: yesThe Lancet
Summary Background Understanding the health consequences associated with exposure to risk factors is necessary to inform public health policy and practice. To systematically quantify the contributions of risk factor exposures to specific health outcomes,
Michael Brauer   +499 more
semanticscholar   +1 more source

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