Results 161 to 170 of about 8,941,456 (288)

Formation of Highly Selective Binding Pockets in UiO‐Type MOFs From Bridged Linkers

open access: yesAngewandte Chemie International Edition, EarlyView.
Much room for design: We present a generalizable strategy for precisely modifying UiO‐type Metal‐organic frameworks with functional groups in a site‐specific manner. Through the use of pre‐connected linkers, pocket‐like pores for molecular recognition are generated.
Tobias Hennig   +7 more
wiley   +1 more source

Deciphering protein mutation-phenotype linkages from CRISPR-based tiling mutagenesis screens. [PDF]

open access: yesCell Syst
He W   +12 more
europepmc   +1 more source

Leveraging Big Multitemporal Multisource Satellite Data and Artificial Intelligence for the Detection of Complex and Invisible Features: The Case of Extensive Irrigation Mapping

open access: yesArchaeological Prospection, EarlyView.
ABSTRACT The detection of buried or obscured archaeological features remains a central challenge in landscape archaeology, particularly in the irrigated floodplains of Mesopotamia where levees and canals formed the basis of complex agrarian systems. This study presents a deep learning–based approach for the large‐scale, automated detection of ancient ...
Nazarij Buławka   +4 more
wiley   +1 more source

Searching for sequence features that control DNA cyclizability. [PDF]

open access: yesPNAS Nexus
Gordiychuk M   +5 more
europepmc   +1 more source

Optimizing Strategies for Non‐Invasive Prospection of Settlements in the Intertidal Zone: A Case Study From the Centre of the Drowned Medieval Village of Tolsende (Scheldt Estuary, the Netherlands)

open access: yesArchaeological Prospection, EarlyView.
ABSTRACT Medieval and early modern drowned villages in the intertidal zone of the Scheldt estuary (the Netherlands) constitute intriguing yet largely understudied components of north‐western Europe's underwater cultural heritage. Despite their high archaeological potential as time capsules of past settlement landscapes, research has remained limited ...
Jan Trachet   +9 more
wiley   +1 more source

CASTOR1 Regulates Humoral Immune Responses and Contributes to the Pathogenesis of Systemic Lupus Erythematosus

open access: yesArthritis &Rheumatology, EarlyView.
Objective CASTOR1 senses arginine and regulates mammalian target of rapamycin complex 1 (mTORC1), a central metabolic signaling molecule. This study aimed to elucidate the roles of CASTOR1 in humoral immune responses. Methods We analyzed human B cell transcriptomes from healthy controls and patients with systemic lupus erythematosus (SLE) via ...
Takeshi Kusuda   +5 more
wiley   +1 more source

Fractal hierarchy enables exponential scaling of topological boundary states. [PDF]

open access: yesNat Commun
Song L   +9 more
europepmc   +1 more source

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