Results 51 to 60 of about 8,470,821 (285)

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

ST-elevation during head up tilt test: a challenging case in syncope unit

open access: yesMonaldi Archives for Chest Disease, 2020
A 65-year-old woman, during an elective head up tilt test, after the sublingual nitrate administration, experienced electrocardiogram alteration with ST elevation in the inferior leads, that returned normal when the patient was laid supine after few ...
Andreina Carbone   +4 more
doaj   +1 more source

Head-Up Tilt in the Nonhuman Primate

open access: yesKidney and Blood Pressure Research, 1984
Experiments were performed to determine the role of the renal nerves in mediating the antinatriuresis of head-up tilt in the nonhuman primate. Male <i>Macaca fascicularis </i>monkeys underwent chronic bilateral renal denervation or sham surgery and were allowed a 1- to 2-week recovery period.
Thomas V. Peterson   +2 more
openaire   +1 more source

Effect of head up tilting on oxygenation [PDF]

open access: yesArchives of Disease in Childhood - Fetal and Neonatal Edition, 2002
We read with interest the paper by Dimitriou et al 1 in which it was confirmed again that head up tilting to 45 degrees results in better oxygenation in stable preterm neonates. However compared with our study,2 in which the same effect was observed, there is a (probably) significant difference.
openaire   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Prolonged Asystole during Head-Up Tilt Test in a Patient with Malignant Neurocardiogenic Syncope

open access: yesJournal of Arrhythmia, 2008
A 27 year-old man was taken to our emergency room after collapsing during a conference. The patient had a history of syncope twice since age 15. A marked sinus bradycardia and asystole were induced causing the patient to collapse when tested to stand up ...
Takashi Tokano, MD   +6 more
doaj   +1 more source

Medium to Long-Term Results of Combined Deltoid and Foot Reconstruction for PCFD (Stage IV) Valgus Ankle

open access: yesFoot & Ankle Orthopaedics, 2022
Category: Ankle; Hindfoot; Other Introduction/Purpose: There is limited documentation of the results of the treatment of advanced progressive collapsing deformity with talar tilt.
Kristin C. Caolo BA   +5 more
doaj   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

DURATION OF HEAD UP TILT TEST FOR EVALUATION OF VASOVAGAL SYNCOPE

open access: yesPakistan Armed Forces Medical Journal, 2019
Objective: To find out the optimum duration of Head up tilt test (HUTT) to produce a positive response in patients with vasovagal syncope. Study Design: Descriptive cross sectional study.
Muhammad Atif Rauf   +4 more
doaj   +2 more sources

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