Results 41 to 50 of about 8,097,891 (280)

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Comparison of short head-up tilt test with conventional protocol after omission of nonmedicated phase in children and young adults

Advanced Biomedical Research, 2016
Background: Syncope is an important and common clinical condition, and the neurally mediated syncope is the most frequent type of syncope. Tilt testing is considered as a first-line diagnostic test.
Bahar Dehghan, Mohammad Reza Sabri
doaj   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Changes in the Index of Cardio-Electrophysiological Balance During the Tilt Table Test in Patients with Altered Level of Consciousness [PDF]

مجله دانشگاه علوم پزشکی گرگان
Background and Objective: The tilt table test is a diagnostic modality used to evaluate patients presenting with altered levels of consciousness (ALOC) or orthostatic symptoms.
Alaleh Farabi•, Hassan Esmaeili•, Mohammad Ali Vakili, Seyed Mehran Hosseini   +3 more
doaj  

Study on Centroid Height Prediction of Non-Rigid Vehicle Based on Deep Learning Combined Model

Sensors
The height of the center of gravity (ZCG) is a critical parameter for evaluating vehicle safety and performance. Systematic errors arise in ZCG measurement via the tilt-table test method due to unlocked suspension systems and variable sprung mass ...
Guoqiang Pang, Zhiquan Xiao, Zhanwen Cai, Pei Wang   +3 more
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Usefulness of Tilt Testing in Children with Syncope: A Survey of Pediatric Electrophysiologists

Indian Pacing and Electrophysiology Journal, 2008
The role of tilt table testing as a diagnostic modality in children with unexplained syncope is unclear. We sent a questionnaire to members of the Pediatric and Congenital Electrophysiology Society to assess the current practice pattern.
Anjan S. Batra, Seshadri Balaji
doaj  

Hemodynamic Response to the Head-Up Tilt Test in Patients With Syncope as a Predictor of the Test Outcome: A Meta-Analysis Approach

Frontiers in Physiology, 2019
Aim: The paper presents a meta-analysis of studies comparing hemodynamic parameters: heart rate (HR), systolic blood pressure (sBP), diastolic blood pressure (dBP), and stroke volume (SV) measured during head-up tilt table test (HUTT) in patients with ...
Katarzyna Buszko, Sławomir Kujawski, Julia L. Newton, Paweł Zalewski   +3 more
doaj   +1 more source

Tilt table testing in neurology and clinical neurophysiology

Clinical Neurophysiology, 2016
Reflex syncope is responsible for 1-6% of hospital admissions and the economic burden of syncope is huge. A considerable part of these high costs is still spent on tests that are not indicated. Till now few neurologists have taken an interest in syncope and tilt table testing (TTT).
Saal, D.P., Thijs, R.D., Dijk, J.G. van
openaire   +4 more sources

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source