Results 11 to 20 of about 2,096 (108)

Identification of circulating T‐cell immunoglobulin and mucin domain 4 as a potential biomarker for coronary heart disease

MedComm, Volume 4, Issue 4, August 2023., 2023
Efferocytosis is inextricably linked to atherosclerosis. TIMD4, a membrane protein mediating efferocytosis, can be cleaved into sTIMD4 by ADAM17. Here, we first reported that sTIMD4 in serum may serve as a biomarker for coronary heart disease. In vitro experiments demonstrated that sTIMD4 formation may be facilitated by activation of p38 mitogen ...
Mengyao Wang, Ke Gong, Xinran Zhu, Shasha Chen, Jie Zhou, Hui Zhang, Jihong Han, Likun Ma, Yajun Duan   +8 more
wiley   +1 more source

Targeting PI3Kγ/AKT Pathway Remodels LC3‐Associated Phagocytosis Induced Immunosuppression After Radiofrequency Ablation

Advanced Science, Volume 9, Issue 7, March 4, 2022., 2022
In hepatocellular carcinoma treated by insufficient radiofrequency ablation, LC3‐associated phagocytosis (LAP) is induced in macrophages, where the macrophages engulf dying tumor cells. Cholesterol efflux during LAP enhances IL‐4 mediated programming and activates the PI3Kγ/AKT pathway.
Xiaodi Liu, Wenyue Zhang, Yanni Xu, Xiaolin Xu, Qiongchao Jiang, Jingliang Ruan, Ye Wu, Yingshi Zhou, Phei Er Saw, Baoming Luo   +9 more
wiley   +1 more source

Kidney Injury Molecule‐1 and Cardiovascular Diseases: From Basic Science to Clinical Practice

BioMed Research International, Volume 2015, Issue 1, 2015., 2015
Despite the recent findings concerning pathogenesis and novel therapeutic strategies, cardiovascular disease (CVD) still stays the leading cause of morbidity and mortality in patients with renal dysfunction, especially acute kidney injury (AKI). Early detection of patients with impaired renal function with cardiovascular risk may help ensure more ...
Branislava Medić, Branislav Rovčanin, Gordana Basta Jovanović, Sanja Radojević-Škodrić, Milica Prostran, Hua Zhue   +5 more
wiley   +1 more source

Multi-scale cluster lens mass mapping I. Strong Lensing modelling

, 2009
We propose a novel technique to refine the modelling of galaxy clusters mass distribution using gravitational lensing. The idea is to combine the strengths of both "parametric" and "non-parametric" methods to improve the quality of the fit.
Bertin, Blandford, Bradač, Bradač, Broadhurst, Clowe, Coe, Czoske, Czoske, de Blok, Deb, Diego, Diego, E. Jullo, Fu, Gavazzi, Gentile, Guzzo, Halkola, Halkola, Hu, J.-P. Kneib, Jee, Jullo, Kassiola, Kneib, Kneib, Koopmans, Liesenborgs, Liesenborgs, Limousin, Limousin, Limousin, Mahdavi, Marshall, Massey, Meneghetti, Natarajan, Navarro, Saha, Salucci, Sand, Schneider, Seljak, Simon, Skilling, Smith, Spergel, Spergel, Suyu, Valenzuela   +50 more
core   +1 more source

Crossover from time-correlated single-electron tunneling to that of Cooper pairs

, 2007
We have studied charge transport in a one-dimensional chain of small Josephson junctions using a single-electron transistor. We observe a crossover from time-correlated tunneling of single electrons to that of Cooper pairs as a function of both magnetic ...
D. V. Averin, D. V. Averin, E. Ben-Jacob, Göran Johansson, J. F. Schneiderman, Jonas Bylander, N. S. Bakhvalov, Per Delsing, Tim Duty   +8 more
core   +1 more source

Binding characteristics of the doxepin E/Z‐isomers to the histamine H1 receptor revealed by receptor‐bound ligand analysis and molecular dynamics study

Journal of Molecular Recognition, Volume 37, Issue 5, September 2024.
Abstract Doxepin is an antihistamine and tricyclic antidepressant that binds to the histamine H1 receptor (H1R) with high affinity. Doxepin is an 85:15 mixture of the E‐ and Z‐isomers. The Z‐isomer is well known to be more effective than the E‐isomer, whereas based on the crystal structure of the H1R/doxepin complex, the hydroxyl group of Thr1123.37 is
Hiroto Kaneko, Ryunosuke Korenaga, Ryota Nakamura, Shinnosuke Kawai, Tadashi Ando, Mitsunori Shiroishi   +5 more
wiley   +1 more source

Geriatrics and Gastroenterology ‐ Time to Wake Up to the Ageing Problem

, 1990
Canadian Journal of Gastroenterology and Hepatology, Volume 4, Issue 6, Page 219-222, 1990.
ABR Thomson
wiley   +1 more source

Soluble immune checkpoint landscape in sickle cell disease links systemic inflammation, autoimmunity, and pain

Frontiers in Hematology
BackgroundSickle cell disease (SCD) is a chronic condition characterized by inflammation, immune dysregulation, and debilitating pain.AimThis study investigates soluble immune checkpoints (sICPs) and their associations with inflammatory mediators, immune
Wei Li, Andrew Q. Pucka, Lina Houran, Xiaoqing Huang, Candice Debats, Brandon A. Reyes, Andrew R. W. O’Brien, Qigui Yu, Ying Wang, Ying Wang   +9 more
doaj   +1 more source

Découverte remarquable dans une grotte du sud-ouest du Maroc : Siagona taggadertensis n.sp. (Carabidae : Siagoninae) [PDF]

, 2011
[EN] Five species of the genus Siagona Latreille 1804 (Carabidae: Siagoninae) are known from Morocco. Siagona taggadertensis n. sp., a remarkable species of Carabidae from a Moroccan cave is described. This insect is spectacular by its large size (one of
Faille, Arnaud, Junger, Bernard
core   +1 more source

03-18-1988 Justice Rehnquist, Per Curiam [PDF]

, 1988
This case involves an attempt by the State of Arkansas to attach certain federal benefits paid to individuals who are incarcerated in Arkansas ...
Rehnquist, William H
core   +1 more source