Results 81 to 90 of about 5,699,484 (294)
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Frontiers in Signal ProcessingDuring cardiac arrhythmia, the heart frequency is an important physiological parameter that can be identified by analyzing electrocardiogram (ECG) signals.
Laura Diaz-Maue +6 more
doaj +1 more source
Parameter Estimation Processor for Chirp Signals Based on a Complex-Valued Deep Neural Network
IEEE Access, 2019 This paper addresses the problem of estimating the parameters of constant-amplitude chirp signals that have single or multiple components and are embedded in noise.
Hanning Su, Qinglong Bao, Zengping Chen
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Time Delay and Frequency Analysis of Remote Microphones
Audiology ResearchBackground/Objectives: A.BA.CO. is a speech-to-text captioning system developed for school classrooms. The system uses remote microphones to capture the teacher’s speech without background noise.
Elena Andreatta +5 more
doaj +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
New algorithms for the analysis of signals with time varying instantaneous frequency [PDF]
, 2006 Yongmei Wei
openalex +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Performance Analysis of High Voltage Insulators Surface Condition Using Time-frequency Distribution [PDF]
, 2013 This paper presents the leakage current of polymeric and non–polymeric insulation materials in contaminated condition. High Density Polyethylene (HDPE) and Polypropylene (PP) are selected as polymeric materials.
Abdullah, Abdul Rahim +4 more
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