Results 121 to 130 of about 5,137,492 (319)

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Research on Coal Gangue Recognition Based on Multi-source Time-Frequency Domain Feature Fusion. [PDF]

ACS Omega, 2023
Zhang Y, Yang Y, Zeng Q.
europepmc   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

COMPARISON BETWEEN TWO DIMENSIONALITY REDUCTION METHODS IN TIME SERIES COMPARACIÓN ENTRE DOS MÉTODOS DE REDUCCIÓN DE DIMENSIONALIDAD EN SERIES DE TIEMPO

Revista Colombiana de Estadística, 2009
Two methods of dimensionality reduction of multivariate stationary time series are analyzed: Peña-Box’s methodology in the time domain and Brillinger’s methodology in the frequency domain.
Zhang Hanwen
doaj  

Evaluating the indicators of a heart rate variability analysis in dogs using Poincaré plots

Veterinární Medicína
Heart rate variability analyses using Poincaré plots can be useful for evaluating the autonomic nervous system function. However, the interpretation of the quantitative indicators of Poincaré plots remains controversial.
T Kimura, S Shimamura, H Sakaya, T Hayashi, A Umemoto, K Sakai, M Yamasaki, T Hasegawa, T Shimada   +8 more
doaj   +1 more source

Deep Learning in Time-Frequency Domain for Document Layout Analysis

, 2021
Felipe Grijalva, Erick Santos, Byron Alejandro Acuña Acurio, Juan Carlos Rodríguez, Julio Larco   +4 more
openalex   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Comparación entre dos métodos de reducción de dimensionalidad en series de tiempo

Revista Colombiana de Estadística, 2009
En este trabajo se analizan dos métodos de reducción de dimensionalidad en series de tiempo multivariadas estacionarias: el método de Peña y Box, basado en el dominio del tiempo, y el método de Brillinger, basado en el dominio de las frecuencias.
HANWEN ZHANG
doaj  

Multi-modal adaptive feature extraction for early-stage weak fault diagnosis in bearings

Electronic Research Archive
We present a novel multi-modal adaptive feature extraction algorithm considering both time-domain and frequency-domain modalities (AFETF), coupled with a Bidirectional Long Short-Term Memory (Bi-LSTM) network based on the Grey Wolf Optimizer (GWO) for ...
Zhenzhong Xu, Xu Chen , Linchao Yang, Jiangtao Xu, Shenghan Zhou   +4 more
doaj   +1 more source

Frequency and Time Domain Analysis ofsRNA-based Treatment for Inflammatory BowelDisease [PDF]

, 2019
Arman Karshenas, Joseph Windo, Bhuvana, Jonathan Stocks, Adrian Kozhevnikov, Jhanna Kryukova, Eleanor Beard, Laurel Constanti Crosby, Max R. Taylor   +8 more
openalex   +1 more source