Results 241 to 250 of about 427,708 (335)

Dynamic Combinatorial Chemistry of Ditellurides

open access: yesChemistry – A European Journal, EarlyView.
Ditelluride exchange. Chemically and structurally diverse ditellurides undergo a rapid Te‐Te exchange under mild reaction conditions in the absence of an external stimulus, indicating that ditellurides could find application in various dynamic molecular systems.
Christian D. Fisker   +3 more
wiley   +1 more source

Development of freezing process of phase change materials in cylindrical thermal energy storage tanks with various fin configurations. [PDF]

open access: yesSci Rep
Abdollahi SA   +6 more
europepmc   +1 more source

Disruption of salt bridge interactions in the inter‐domain cleft of the tubulin‐like protein FtsZ of Escherichia coli makes cells sensitive to the cell division inhibitor PC190723

open access: yesCytoskeleton, EarlyView.
Abstract FtsZ forms a ring‐like assembly at the site of division in bacteria. It is the first protein involved in the formation of the divisome complex to split the cell into two halves, indicating its importance in bacterial cell division. FtsZ is an attractive target for developing new anti‐microbial drugs to overcome the challenges of antibiotic ...
Sakshi Mahesh Poddar   +3 more
wiley   +1 more source

Ultrafast phonon-mediated dephasing of color centers in hexagonal boron nitride probed by electron beams. [PDF]

open access: yesNat Commun
Taleb M   +9 more
europepmc   +1 more source

Synthesis, Antimycobacterial Activity, and Computational Insight of Novel 1,4‐Benzoxazin‐2‐one Derivatives as Promising Candidates against Multidrug‐Resistant Mycobacterium Tuberculosis

open access: yesChemMedChem, EarlyView.
A series of 14 novel 1,4‐benzoxazinone derivatives is tested against various strains of Mycobacterium tuberculosis. All compounds show high activity against all tested strains, particularly the resistant strains. Additionally, the novel derivatives exhibit low cytotoxicity toward mammalian Vero cells.
Maria Grazia Mamolo   +6 more
wiley   +1 more source

Is Mycobacterial InhA a Suitable Target for Rational Drug Design?

open access: yesChemMedChem, EarlyView.
InhA is the target of isoniazid, a first‐line antituberculosis drug. Isoniazid is, in fact, a prodrug that needs to be activated. Researchers are trying to develop direct inhibitors of InhA. This includes the resolution of crystallographic structures. The Protein Data Bank contains over a hundred InhA structures.
Julien Rizet   +7 more
wiley   +1 more source

Temperature Dependence of Nonlinear Elastic Moduli of Polystyrene. [PDF]

open access: yesPolymers (Basel)
Belashov AV   +3 more
europepmc   +1 more source

Novel Quinazolinones Active against Multidrug‐Resistant Mycobacterium Tuberculosis: Synthesis, Antimicrobial Evaluation, and in Silico Exploration of Penicillin‐Binding Protein 1A as a Potential Target

open access: yesChemMedChem, EarlyView.
Quinazolinone‐based compounds emerge as potent antimycobacterial agents, showing low minimum inhibitory concentrations against drug‐resistant Mycobacterium tuberculosis. Molecular modeling uncovers a novel allosteric site in PonA1 targeted by these derivatives.
Marek Kerda   +15 more
wiley   +1 more source

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