Results 61 to 70 of about 427,708 (335)
NAD+ regeneration by mitochondrial complex I NADH dehydrogenase is important for cancer cell proliferation. Specifically, NAD+ is necessary for the activities of NAD+‐dependent deacetylases SIRT3 and SIRT7, which suppress the expression of p21Cip1 cyclin‐dependent kinase inhibitor, an antiproliferative molecule, at the translational and transcriptional
Masato Higurashi+5 more
wiley +1 more source
Molecular Dynamics Computer Simulation of the Dynamics of Supercooled Silica
We present the results of a large scale computer simulation of supercooled silica. We find that at high temperatures the diffusion constants show a non-Arrhenius temperature dependence whereas at low temperature this dependence is also compatible with an
Angell C. A.+8 more
core +1 more source
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen+12 more
wiley +1 more source
Backward correlations and dynamic heterogeneities: a computer study of ion dynamics
We analyse the correlated back and forth dynamics and dynamic heterogeneities, i.e. the presence of fast and slow ions, for a lithium metasilicate system via computer simulations.
A. Heuer+34 more
core +1 more source
Damage detections in nonlinear vibrating thermally loaded plates [PDF]
In this work, geometrically nonlinear vibrations of fully clamped rectangular plates subjected to thermal changesare used to study the sensitivity of some vibration response parameters to the presence of damage and elevated temperature. The geometrically
A.R. Kukreti+18 more
core +2 more sources
Mechanisms of De‐icing by Surface Rayleigh and Plate Lamb Acoustic Waves
Ice accretion impacts daily life, renewable energy generation, maintenance, and security in industries and aeronautics. Acoustic waves (AW) are a promising method for ice removal, although de‐icing mechanisms require further investigation to optimize energy efficiency.
Shilpi Pandey+15 more
wiley +1 more source
Rheological Master Curves of Crystallizing Polymer Mixtures
We present a simple methodology for extending linear viscoelastic measurements of crystallizing polymers to the high-frequency regime, where usually crystallization kinetics represents an obstacle. The idea is to perform rapid quenches, below the melting
Kapnistos M., Vlassopoulos D.
doaj +1 more source
Study on Mechanical Relaxations of 7075 (Al–Zn–Mg) and 2024 (Al–Cu–Mg) Alloys by Application of the Time-Temperature Superposition Principle [PDF]
The viscoelastic response of commercial Al–Zn–Mg and Al–Cu–Mg alloys was measured with a dynamic-mechanical analyzer (DMA) as a function of the temperature (from 30 to 425ºC) and the loading frequency (from 0.01 to 150 Hz).
Crespo Artiaga, Daniel+2 more
core +4 more sources
This study explores the energy conversion in powder bed fusion of polymers using laser beam for polyamide 12 and polypropylene powders. It combines material and process data, using dimensionless parameters and numerical models, to enable the prediction of suitable printing parameters.
Christian Schlör+9 more
wiley +1 more source
Formulation of non-linear viscoelastic–viscoplastic constitutive equation for polyamide 6 resin
In this study, a non-linear viscoelastic–viscoplastic constitutive equation for polyamide 6 (PA6) is formulated and a new model is suggested for the viscoplastic part of the equation.
Jun Koyanagi+4 more
doaj