Results 61 to 70 of about 633,071 (308)

AN EFFICIENT METHOD TO EVALUATE AND ENHANCE SPORT JUDGES’ PERFORMANCE DURING COMPETITION: A CASE STUDY IN ACROBATIC GYMNASTICS

Science of Gymnastics Journal
Who judges the gymnastics judges? How do we measure their accuracy and concordance? How do we know if the judging process is fair? The superior jury has this responsibility.
Juan Antonio Leon - Prados, Carmen Ramos
doaj   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

Using Evolutionary Spectra to Forecast Time Series [PDF]

In this paper, an adaptive smoothing forecasting approach based on evolutionary spectra as developed by Rao and Shapiro (1970) is applied to the 3003 time series of various types and lengths used in the M3-Competition (Makridakis and Hibon, 2000 ...
Elizabeth Ann Maharaj
core  

Developing a typology of competition and growth strategies based on the use of artificial intelligence

π-Economy
The goal of this study is to develop a typology of competition and growth strategies based on the use of artificial intelligence (AI), using examples of the strategic development of the largest retail grocery chains as representatives of a ...
Krasyuk Tatyana
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Scheduled Delays? Scheduled Time Competition and On-Time Performance in the Airline Industry. [PDF]

No abstractTime competition, on-time performance,
Yan Dong, Kefeng Xu
core  

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Competition Policy in Georgia – The Major Phases of Development [PDF]

, 2019
The article analyzes and discusses the possibilities of competition policy in Georgia. The study uses economic analysis. The article based on the facts of the Georgian market. Nowadays, Georgia has a highly liberalized economy with few ...
Nika Asanidze
core   +1 more source

Empirical Measurement of Competition in the Thai Banking Industry

Economies, 2020
The degree of competition in the banking industry can be observed and measured by two approaches, structural and nonstructural. Based on these two approaches, there are various indicators, which are different factors and methods.
Jirawan Prayoonrattana, Thanarak Laosuthi, Bundit Chaivichayachat   +2 more
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source