Results 121 to 130 of about 13,838,030 (309)

The time-domain response of coupled-resonator filters with applications to tuning [PDF]

, 2004
This thesis develops a new theory of tuning filters based on the time-domain response of the filter. These methods are shown to work very well for all-pole coupledresonator filters in particular, and may be applied to automated tuning of filters ...
Dunsmore, Joel Philip
core  

Feedback Beamforming in the Time Domain

Sensors
Real-time source localization is crucial for high-end automation and artificial intelligence (AI) products. However, a low signal-to-noise ratio (SNR) and limited processing time can reduce localization accuracy. This work proposes a new architecture for a time-domain feedback-based beamformer that meets real-time processing demands. The main objective
Zvi Aharon Herscovici, Israel Cohen
openaire   +3 more sources

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Utilizing MRAMs With Low Resistance and Limited Dynamic Range for Efficient MAC Accelerator

IEEE Open Journal of Nanotechnology
The recent advancements in data mining, machine learning algorithms and cognitive systems have necessitated the development of neuromorphic processing engines which may enable resource and computationally intensive applications on the internet-of-Things (
Sateesh, Kaustubh Chakarwar, Shubham Sahay   +2 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Lens Alternatives to Microscope Objectives in Optical Coherence Microscopy for Ultra-High-Resolution Imaging

Photonics
Ultrahigh lateral resolution (UHLR) optical coherence tomography (OCT) technology, also called optical coherence microscopy (OCM), has gained popularity, especially in the field of biomedical imaging.
Xinjie Zhu, Zijian Zhang, Samuel Lawman, Xingyu Yang, Yalin Zheng, Yaochun Shen   +5 more
doaj   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Evaluating the indicators of a heart rate variability analysis in dogs using Poincaré plots

Veterinární Medicína
Heart rate variability analyses using Poincaré plots can be useful for evaluating the autonomic nervous system function. However, the interpretation of the quantitative indicators of Poincaré plots remains controversial.
T Kimura, S Shimamura, H Sakaya, T Hayashi, A Umemoto, K Sakai, M Yamasaki, T Hasegawa, T Shimada   +8 more
doaj   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

FDTD channel modelling with time domain huygens' technique

, 2011
Much interest is currently being shown in mm-wave high data rate, short range communication links. The modelling of these types of links presents considerable challenges.
Paul, DL, Dumanli, S, Railton, CJ
core