Wave separation in the trumpet under playing conditions and comparison with time domain finite difference simulation [PDF]
Wave separation within a trumpet is presented using three high pressure microphones to measure pressure waves within the curved, constant cross-section tuning slide of the instrument while the instrument was being played by a virtuoso trumpet player.
Kemp, Jonathan A +9 more
core +1 more source
Asymptotic Performance Analysis of Time-Frequency-Domain Spread MC DS-CDMA Systems Employing MMSE Multiuser Detection [PDF]
In this contribution the asymptotic signal-to-interference-plus-noise ratio (SINR) performance of multicarrier direct-sequence code-division multiple-access systems employing time-frequency-domain spreading, i.e., of the TF/MC DS-CDMA systems, is studied,
Zhang, Youguang +5 more
core +2 more sources
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
FDTD channel modelling with time domain huygens' technique [PDF]
Much interest is currently being shown in mm-wave high data rate, short range communication links. The modelling of these types of links presents considerable challenges.
Paul, DL, Dumanli, S, Railton, CJ
core
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
An Investigation of the Accuracy of Finite-Volume Radial Domain Truncation Technique [PDF]
© Copyright 2007 IEEE. Personal use of this material is permitted. However, permission to reprint/republish this material for advertising or promotional purposes or for creating new collective works for resale or redistribution to servers or lists, or to
Vahldieck, R. +5 more
core +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Distributed-memory parallelization of an explicit time-domain volume integral equation solver on Blue Gene/P [PDF]
Two distributed-memory schemes for efficiently parallelizing the explicit marching-on in-time based solution of the time domain volume integral equation on the IBM Blue Gene/P platform are presented.
Cheeseman, M, Bağcı, H, Al-Jarro, A
core
Epigenetic reprogramming of lineage switching in cancer
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source

