Results 91 to 100 of about 18,891,715 (293)
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Terahertz Time Domain Spectrometer
, 2014 In the framework of the European Metrology Research Program Project NEW-07 “Microwave and Terahertz metrology for homeland security”, a Time Domain Spectrometer working up to about 3 THz has been realized.
OBERTO, LUCA, BISI, MARCO
core
Time-domain braiding of anyons
ScienceAnyons are quasiparticles that keep a robust memory of particle exchanges via a braiding phase factor. When an anyon excitation is emitted toward a quantum point contact (QPC) in a fractional quantum Hall (FQH) fluid, this memory translates into tunneling events that may occur long after the anyon excitation has exited the QPC.
Ruelle, M. +13 more
openaire +4 more sources
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Feedback Beamforming in the Time Domain
SensorsReal-time source localization is crucial for high-end automation and artificial intelligence (AI) products. However, a low signal-to-noise ratio (SNR) and limited processing time can reduce localization accuracy. This work proposes a new architecture for a time-domain feedback-based beamformer that meets real-time processing demands. The main objective
Zvi Aharon Herscovici, Israel Cohen
openaire +4 more sources
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
FDTD channel modelling with time domain huygens' technique [PDF]
, 2011 Much interest is currently being shown in mm-wave high data rate, short range communication links. The modelling of these types of links presents considerable challenges.
Paul, DL, Dumanli, S, Railton, CJ
core
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
The Role of Probe Attenuation in the Time-Domain Reflectometry Characterization of Dielectrics [PDF]
, 2010 The influence of the measurement setup on the estimation of dielectric permittivity spectra from time-domain reflectometry (TDR) responses is investigated.
Ferraris, S. +6 more
core +1 more source