Results 131 to 140 of about 15,732,617 (305)

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

A practical method for the detection of freezing of gait in patients with Parkinson’s disease

open access: yesClinical Interventions in Aging, 2014
Yuri Kwon,1 Sang Hoon Park,1 Ji-Won Kim,1 Yeji Ho,1 Hyeong-Min Jeon,1 Min-Jung Bang,1 Gu-In Jung,1 Seon-Min Lee,3 Gwang-Moon Eom,1,2 Seong-Beom Koh,3 Jeong-Whan Lee,1,2 Heung Seok Jeon41Biomedical Engineering, 2Research Institute of Biomedical ...
Kwon Y   +11 more
doaj  

Evaluating the indicators of a heart rate variability analysis in dogs using Poincaré plots

open access: yesVeterinární Medicína
Heart rate variability analyses using Poincaré plots can be useful for evaluating the autonomic nervous system function. However, the interpretation of the quantitative indicators of Poincaré plots remains controversial.
T Kimura   +8 more
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Time-domain simulations for floating structures [PDF]

open access: yes, 2009
In this thesis numerical and analytical investigations of wave-structure interactions are conducted within the linearised theory of water waves. The primary objective of the thesis was to develop a numerical time-domain solution method capable of ...
Colm J. Fitzgerald (7158557)
core  

Measuring Online Battery AC Resistance Using a DC-DC Converter With Time and Frequency Hybrid Method

open access: yesIEEE Access
The estimation of battery state is important for ensuring the stability of batteries. The AC resistance of a battery is one of the factors used to estimate the battery state, and is measured using a Fast Fourier Transform (FFT), a technique that analyzes
Seong-Jong Kim   +3 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Under the Clouds of War

open access: yes, 1972
Consists of film clips of World War II events, including Mussolini\u27s invasion of Ethiopia and Hitler\u27s march into Austria.
Time-Life Video
core  

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