Results 61 to 70 of about 18,851,731 (293)

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Implementation of wavelet transform based on switched current circuits

open access: yesDianzi Jishu Yingyong, 2018
In order to meet the engineering application requirement for low-power and real-time signal processing, an implementation of wavelet transform using switched current(SI) technique is presented in this paper.
Hu Qinchun   +5 more
doaj   +1 more source

Microwave Angiography by Ultra-Wideband Sounding: A Preliminary Investigation

open access: yesDiagnostics, 2023
Angiography is a very informative method for physicians such as cardiologists, neurologists and neuroscientists. The current modalities experience some shortages, e.g., ultrasound is very operator dependent.
Somayyeh Chamaani   +5 more
doaj   +1 more source

Time-Domain Filtering of Metasurfaces [PDF]

open access: yesScientific Reports, 2015
AbstractIn general electromagnetic response of each material to a continuous wave does not vary in time domain if the frequency component remains the same. Recently, it turned out that integrating several circuit elements including schottky diodes with periodically metallised surfaces, or the so-called metasurfaces, leads to selectively absorbing ...
openaire   +2 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Free Surface Reconstruction for Phase Accurate Irregular Wave Generation

open access: yesJournal of Marine Science and Engineering, 2018
The experimental wave paddle signal is unknown to the numerical modellers in many cases. This makes it quite challenging to numerically reproduce the time history of free surface elevation for irregular waves.
Ankit Aggarwal   +4 more
doaj   +1 more source

Time-domain studies of M31 [PDF]

open access: yesAstronomical Review, 2016
M31, our closest neighboring galaxy, is a stepping stone to studies of stellar evolution, star formation, galaxy evolution, and cosmology. However, due to the difficulties of performing photometry in such crowded fields and the lack of wide cameras to encompass the entire galaxy, there has not been a complete census of the stellar contents of M31.
openaire   +2 more sources

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Faster 3D finite element time domain : Floquet absorbing boundary condition modelling using recursive convolution and vector fitting [PDF]

open access: yes, 2009
A recursive convolution (RC) based on the vector fitting (VF) method and triangular temporal basis functions is employed to compute the Floquet absorbing boundary condition (FABC) formulation in the vector 3D finite element time-domain (FETD) modelling ...
Cai, Yong, Mias, Christos
core   +1 more source

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