Results 101 to 110 of about 18,851,731 (293)

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Utilizing MRAMs With Low Resistance and Limited Dynamic Range for Efficient MAC Accelerator

IEEE Open Journal of Nanotechnology
The recent advancements in data mining, machine learning algorithms and cognitive systems have necessitated the development of neuromorphic processing engines which may enable resource and computationally intensive applications on the internet-of-Things (
Sateesh, Kaustubh Chakarwar, Shubham Sahay   +2 more
doaj   +1 more source

A Time-Domain CMOS Oscillator-Based Thermostat with Digital Set-Point Programming

Sensors, 2013
This paper presents a time-domain CMOS oscillator-based thermostat with digital set-point programming [without a digital-to-analog converter (DAC) or external resistor] to achieve on-chip thermal management of modern VLSI systems.
Shih-Hao Lin, Chun-Chi Chen
doaj   +1 more source

Time-domain braiding of anyons

Science
Anyons are quasiparticles that keep a robust memory of particle exchanges via a braiding phase factor. When an anyon excitation is emitted toward a quantum point contact (QPC) in a fractional quantum Hall (FQH) fluid, this memory translates into tunneling events that may occur long after the anyon excitation has exited the QPC.
Ruelle, M., Frigerio, E., Baudin, E., Berroir, J.-M., Plaçais, B., Grémaud, B., Jonckheere, T., Martin, T., Rech, J., Cavanna, A., Gennser, U., Jin, Y., Ménard, G., Fève, G.   +13 more
openaire   +4 more sources

An Investigation of the Accuracy of Finite-Volume Radial Domain Truncation Technique [PDF]

, 2007
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Vahldieck, R., Christophe Fumeaux, Sankaran, K., Fumeaux, C., Krishnaswamy Sankaran, Rudiger Vahldieck   +5 more
core   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Lens Alternatives to Microscope Objectives in Optical Coherence Microscopy for Ultra-High-Resolution Imaging

Photonics
Ultrahigh lateral resolution (UHLR) optical coherence tomography (OCT) technology, also called optical coherence microscopy (OCM), has gained popularity, especially in the field of biomedical imaging.
Xinjie Zhu, Zijian Zhang, Samuel Lawman, Xingyu Yang, Yalin Zheng, Yaochun Shen   +5 more
doaj   +1 more source