Results 91 to 100 of about 15,732,617 (305)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Reliability-Aided Multiuser Detection in Time-Frequency-Domain Spread Multicarrier DS-CDMA Systems

open access: yes, 2009
In this contribution we propose and study a novel multiuser detection (MUD) scheme for multicarrier direct-sequence code-division multiple-access systems employing both time (T)-domain and frequency (F)-domain spreading, which are referred to as the TF ...
Yang, Lie-Liang   +5 more
core   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

A causal model for linear RF systems developed from frequency-domain measured data [PDF]

open access: yes, 2005
With the ever-growing complexity of interconnect networks, models developed from measured data or data from 3-D electromagnetic simulators are increasingly becoming essential. It is to this end that the current contribution is directed. In particular, it
Condon, Marissa   +2 more
core   +2 more sources

Topology optimization of dispersive plasmonic nanostructures in the time-domain

open access: yes, 2022
Topology optimization techniques have been applied in integrated optics and nanophotonics for the inverse design of devices with shapes that cannot be conceived by human intuition.
Antonio Calà Lesina (14409222)   +1 more
core   +1 more source

Issues in Planning Domain Model Engineering [PDF]

open access: yes
The paper raises some issues relating to the engineering of domain models for automated planning. It studies the idea of a domain model as a formal specification of a domain, and considers properties of that specification.
Vallati, Mauro   +2 more
core   +1 more source

The time-domain response of coupled-resonator filters with applications to tuning [PDF]

open access: yes, 2004
This thesis develops a new theory of tuning filters based on the time-domain response of the filter. These methods are shown to work very well for all-pole coupledresonator filters in particular, and may be applied to automated tuning of filters ...
Dunsmore, Joel Philip
core   +2 more sources

Time domain optical sensing

open access: yes1999 IEEE LEOS Annual Meeting Conference Proceedings. LEOS'99. 12th Annual Meeting. IEEE Lasers and Electro-Optics Society 1999 Annual Meeting (Cat. No.99CH37009), 1999
A chirped optical supercontinuum is used to map absorption spectra into temporal waveforms. Time-domain spectral measurement of acetylene is demonstrated using a modelocked fibre laser as the source of broadband radiation and a sampling oscilloscope for spectral measurement.
P.V. Kelkar   +3 more
openaire   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

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