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Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
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Time-frequency analysis reveals an association between the specific nuclear magnetic resonance (NMR) signal properties of serum samples and arteriosclerotic lesion progression in a diabetes mouse model. [PDF]
PLoS OneYui K +4 more
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Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
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A method for time-frequency analysis
IEEE Transactions on Signal Processing, 1994A method for time-frequency signal analysis is presented. The proposed method belongs to the general class of smoothed pseudo Wigner distributions. It is derived from the analysis of the Wigner distribution defined in the frequency domain. This method provides some substantial advantages over the Wigner distribution.
Ljubisa Stanković
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The beginning of time-frequency analysis
The Journal of the Acoustical Society of America, 2022The Reflections series takes a look back on historical articles from The Journal of the Acoustical Society of America that have had a significant impact on the science and practice of acoustics.
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IEEE Signal Processing Magazine, 1999
It has been well understood that a given signal can be represented in an infinite number of different ways. Different signal representations can be used for different applications. For example, signals obtained from most engineering applications are usually functions of time. But when studying or designing the system, we often like to study signals and
Shie Qian, Dapang Chen
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It has been well understood that a given signal can be represented in an infinite number of different ways. Different signal representations can be used for different applications. For example, signals obtained from most engineering applications are usually functions of time. But when studying or designing the system, we often like to study signals and
Shie Qian, Dapang Chen
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Time--frequency analysis of biosignals
IEEE Engineering in Medicine and Biology Magazine, 2009The wavelet transform has a powerful time-frequency analysis and signal-coding tool suitable for use in the manipulation of complex nonstationary signals. This article provides an overview of the emerging role of wavelet-transform analysis in biomedical signal processing and analysis.
Addison, Paul +2 more
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Wavelets and time-frequency analysis
Proceedings of the IEEE, 1996We present a selective overview of time-frequency analysis and some of its key problems. In particular we motivate the introduction of wavelet and wavelet packet analysis. Different types of decompositions of an idealized time-frequency plane provide the basis for understanding the performance of the numerical algorithms and their corresponding ...
Nikolaj Hess-Nielsen +1 more
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