Results 141 to 150 of about 2,232,503 (310)

High frequency correlation modelling [PDF]

open access: yes
Many statistical arbitrage strategies, such as pair trading or basket trading, are based on several assets. Optimal execution routines should also take into account correlation between stocks when proceeding clients orders.
Frédéric Abergel, Nicolas Huth
core  

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

Evaluation of Fiber Optic Time and Frequency Distribution System in a Coherent Communication Network

open access: yes, 2019
A fiber-based time transfer between UTC(SP) and the VLBI-station at Onsala Space Observatory has been evaluated. The transfer uses a single wavelength in an active coherent DWDM-network in unidirectional duplex fibers and is routed through Reconfigurable
Carsten Rieck   +11 more
core   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Feasibility of high frequency alternating current power distribution for the automobile auxiliary electrical system [PDF]

open access: yes, 2011
This study investigates the feasibility and potential benefits of high frequency alternating current (HFAC) for vehicle auxiliary electrical systems. A 100Vrms, 50kHz sinusoidal AC bus is compared with 14V DC and 42V DC electrical systems in terms of ...
Antaloae, C. C.
core  

ECG arrhythmia classification using time frequency distribution techniques. [PDF]

open access: yesBiomed Eng Lett, 2017
Sultan Qurraie S, Ghorbani Afkhami R.
europepmc   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

Proofs for Discrete Time-Frequency Distribution Properties [PDF]

open access: yes, 2009
This technical report contains proofs for a set of mathematical properties of a recently proposed discrete time-frequency distribution ...
O' Toole, John M.   +2 more
core  

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