Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende +26 more
wiley +1 more source
Impact of an Ambient AI Scribe Among Clinicians and Patients: Real-World Prospective Observational Time-Motion Study. [PDF]
Tan JYE +9 more
europepmc +1 more source
ABSTRACT Background Accessing brain magnetic resonance imaging (MRI) can be challenging, especially for underserved patients, which may lead to disparities in neurological diagnosis. Method This mixed‐methods study enrolled adults with one of four neurological disorders: mild cognitive impairment or dementia of the Alzheimer type, multiple sclerosis ...
Maya L. Mastick +19 more
wiley +1 more source
Intelligent Dental Handpiece: Real-Time Motion Analysis for Skill Development. [PDF]
Sallam M +5 more
europepmc +1 more source
Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher +10 more
wiley +1 more source
Real-Time Motion Compensation for Dynamic Dental Implant Surgery. [PDF]
Pisla D +9 more
europepmc +1 more source
Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett +8 more
wiley +1 more source
A time-motion study of community health workers delivering community-based primary health care in Neno District, Malawi. [PDF]
Aron MB +6 more
europepmc +2 more sources
Time Savings Through an AI Speech Assistant for Nursing Documentation: Pre-Post Time-Motion Study in German Long-Term Care. [PDF]
Schwabe K +4 more
europepmc +1 more source
The Purpose of Time-Motion Studies (TMSs) in Healthcare: A Literature Review. [PDF]
Kalne PS, Mehendale AM.
europepmc +1 more source

