Results 71 to 80 of about 11,557,266 (316)
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Generating 3D product design models in real-time using hand motion and gesture
, 2010 This thesis was submitted for the degree of Master of Philosophy and awarded by Brunel University.Three dimensional product design models are widely used in conceptual design and in the early stage of prototyping during the design processes.
Orphanides, Stephan
core
A LQR washout algorithm for a driving simulator equipped with a hexapod platform : the relationship of neuromuscular dynamics with the sensed illness rating [PDF]
, 2012 This study proposes a method and an experimental validation to analyze dynamics response of the drivers with respect to the type of the control used in the hexapod driving simulator.
KEMENY, Andras +3 more
core
Motion extrapolation in the central fovea [PDF]
, 2012 Neural transmission latency would introduce a spatial lag when an object moves across the visual field, if the latency was not compensated. A visual predictive mechanism has been proposed, which overcomes such spatial lag by extrapolating the position of
Nijhawan, Romi +7 more
core +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Routledge Open ResearchPlaying music as part of a group is challenging, but also rewarding. What factors come together to maximize rewarding group playing experiences? How do feelings of enjoyment, frustration, and social (dis)connection shape group performance as it unfolds ...
Laura Bishop
doaj +1 more source
Real-time motion amplification on mobile devices
, 2022 Abstract A simple motion amplification algorithm suitable for real-time applications on mobile devices is presented. It is based on motion enhancement by moving average differencing (MEMAD), a temporal high-pass filter for video streams. MEMAD can amplify small moving objects or subtle motion in larger objects.
openaire +2 more sources
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Routledge Open ResearchThis paper presents a model of musical togetherness (MT), defined as the sense of musical connection that arises during real-time interaction and results in feelings of social connection, pleasure, and trust. The model comprises three layers.
Laura Bishop
doaj +1 more source