Embedded CRISPRi Enhances Gene‐Silencing Efficiency in Drosophila
Current CRISPR interference (CRISPRi) technology in Drosophila has limited efficiency. This study introduces the emCRISPRi platform, which significantly enhances transcriptional silencing efficacy by embedding inhibitory domains within the dCas9 architecture.
Pengchong Fu +7 more
wiley +1 more source
Reconstruction techniques in nuclear medicine time-of-flight PET [PDF]
Vandenberghe, Stefaan
core +1 more source
Flying High: Isometric Strength Training Increases Time of Flight in Junior Elite Trampoline Gymnasts. [PDF]
Dyas N +5 more
europepmc +1 more source
We identify a Lepidoptera‐conserved testis‐specific arylalkylamine N‐acetyltransferase (LTNAT) that governs male moth fertility via a novel mechanism. LTNAT loss disrupts eupyrene sperm mitochondrial derivatives and impairs apyrene sperm motility, offering a safe molecular target for innovative pesticides and genetic pest control.
Hao Sun +5 more
wiley +1 more source
Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry: A breakthrough in rapid and precise mold identification. [PDF]
Naik A +5 more
europepmc +1 more source
Machine Learning for Green Solvents: Assessment, Selection and Substitution
Environmental regulations have intensified demand for green solvents, but discovery is limited by Solvent Selection Guides (SSGs) that quantify solvent sustainability. Training a machine learning model on GlaxoSmithKline SSG, a database of sustainability metrics for 10,189 solvents, GreenSolventDB is developed. Integrated with Hansen solubility metrics,
Rohan Datta +4 more
wiley +1 more source
Association of carotid artery stenosis with cerebral artery signal intensity gradient on time-of-flight magnetic resonance angiography. [PDF]
Lee CH +5 more
europepmc +1 more source
Nitrosyl heme emerges as an extracellular nitrodilator that dilates arteries without crossing the cell membrane. Instead, heme‐NO mobilizes NO moieties from a preformed intracellular NO store within vascular smooth muscle, providing both functional and chemical evidence for the NANOS model, revealing a previously unrecognized mechanism of arterial ...
Taiming Liu +9 more
wiley +1 more source
Time-of-flight camera achieves high diagnostic accuracy in adolescent idiopathic scoliosis: a promising radiation-free alternative to radiography. [PDF]
Boché A +5 more
europepmc +1 more source

