Results 91 to 100 of about 20,295,200 (307)
, 1972 Consists of film clips of World War II events, including Mussolini\u27s invasion of Ethiopia and Hitler\u27s march into Austria.
Time-Life Video
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Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
SensorsIn this work, we propose a robust deep encoder–decoder neural network that integrates multiple deep sequence models for time series forecasting in sensor-based applications.
Hsu-Yung Cheng +3 more
doaj +1 more source
SARIMA Approach to Generating Synthetic Monthly Rainfall in the Sinú River Watershed in Colombia
Atmosphere, 2020 Seasonal Auto Regressive Integrative Moving Average models (SARIMA) were developed for monthly rainfall time series. Normality of the rainfall time series was achieved by using the Box Cox transformation.
Luisa Martínez-Acosta +4 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Wrapper Feature Extraction for Time Series Classification Using Singular Value Decomposition [PDF]
, 2005 Time series classification is an important aspect of time series mining. Recently, time series classification has attracted increasing interests in various domains. However, the high dimensionality property of time series makes time series classification
Hui, Zhang, Kawasaki, Saori, Tu, Bao Ho
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Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Modelling Time Series Extremes
Revstat Statistical Journal, 2012 The need to model rare events of univariate time series has led to many recent advances in theory and methods. In this paper, we review telegraphically the literature on extremes of dependent time series and list some remaining challenges.
V. Chavez-Demoulin , A.C. Davison
doaj +1 more source