Results 91 to 100 of about 18,915,989 (297)
Time-Varying Beta Estimators in the Mexican Emerging Market [PDF]
This paper compares the performance of three different time-varying betas that have never previously been compared: the rolling OLS estimator, a nonparametric estimator and an estimator based on GARCH models. The study is conducted using returns from the
Nieto Domenech, Belén +2 more
core
Introduction: Tricyclic antidepressant have been shown to be effective in treatment of pain of varying etiology, monoaminergic system seems to be implicated in this phenomena.
H A Zawia, F A Blaou, A S Elhwuegi
doaj +1 more source
Mitochondrial translation and coordinated cytosolic translation in metabolic homeostasis and disease
Mitochondrial function depends on coordinated protein production from the nuclear and mitochondrial genomes. This review highlights how cytosolic and mitochondrial translation, mRNA localization, protein import, and respiratory complex assembly are integrated to maintain mitochondrial proteostasis and function.
Boseon Kim +4 more
wiley +1 more source
Input-to-state stability for discrete-time time-varying systems with applications to robust stabilization of systems in power form [PDF]
Input-to-state stability (ISS) of a parameterized family of discrete-time time-varying nonlinear systems is investigated. A converse Lyapunov theorem for such systems is developed.
Laila, D. S. +5 more
core +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Systematic risk analysis: first steps towards a new definition of beta [PDF]
We suggest a new model-free definition of the beta coefficient, which plays an important rôle in systematic risk management. This setting, which is based on the existence of trends for financial time series via nonstandard analysis (Fliess M., Join C.: A
Michel Fliess, Cédric Join
core
IntroductionThe Integration of functional magnetic resonance imaging (fMRI) and electroencephalography (EEG) has allowed for a novel exploration of the brain’s spatial–temporal resolution.
Souvik Phadikar +3 more
doaj +1 more source
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Disaggregated ESG Risk in European Asset Pricing Based on ESG Leaders Data [PDF]
Background: This study investigates the conditional pricing of environmental, social, governance (ESG)-related risk exposures – specifically ESG, carbon intensity, and controversy – using portfolio-level data from firms in the Morgan Stanley Capital ...
Salzmann, Eleonora
doaj +1 more source
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source

