Results 171 to 180 of about 18,915,989 (297)

In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols

FEBS Open Bio, EarlyView.
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton, Fang Zhao, Reeta Davis, Meg Walsh, Kevin E O'Connor, David O'Connell, Tanja Narancic   +6 more
wiley   +1 more source

Time-varying continuous and jump betas: the role of firm characteristics and periods of stress

, 2017
Using high frequency data we decompose the time-varying beta for stocks into beta for continuous systematic risk and beta for discontinuous systematic risk.
W Yao (13658707), V Alexeev (13656697), M Dungey (7711058)   +2 more
core  

Drivers of Black-White Disparities in Hypertension Risk After Pregnancy: Findings From CARDIA. [PDF]

Circ Popul Health Outcomes
Borrowman JD, Cai X, Lane AD, Harville EW, N Kershaw K, Carnethon MR.   +5 more
europepmc   +1 more source

Adenosine triphosphate as a modulator of protein interactions and stability

FEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

Evaluation of PainWaive: a consumer-grade EEG headset for remote EEG monitoring and neurofeedback research in chronic pain. [PDF]

NPJ Digit Med
Chowdhury NS, Rawsthorne J, Hesam-Shariati N, Quidé Y, Alexander L, Ermolenko E, McIntyre A, Restrepo S, Chen K, Lin CT, Newton-John T, Middleton JW, Craig A, Jensen MP, McAuley JH, Gustin SM.   +15 more
europepmc   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

FEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen, Robin Romein, Willy A. M. van den Berg, Simon Lindhoud, Jan Willem Borst, Carlo P. M. van Mierlo   +5 more
wiley   +1 more source

Design and model choices shape inference of age-varying genetic effects on complex traits. [PDF]

Nat Aging
Schoeler T, Wiegrebe S, Winkler TW, Kutalik Z.   +3 more
europepmc   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

Time-varying beta and the Asian financial crisis: Evidence from the Asian industrial sectors

This paper empirically investigates the effects of the Asian financial crisis of 1997-98, and the period immediately afterwards, on the time-varying beta of four industrial sectors (chemical, finance, retail and industry) of Indonesia, Singapore, South ...
Peng, Ke, Choudhry, Taufiq, Lu, Lin
core  

Coupled beta and high-frequency oscillations emerge from synchronized bursting in a minimal model of the parkinsonian subthalamic nucleus. [PDF]

PLoS Comput Biol
Sheheitli H, Johnson LA, Wang J, Aman JE, Vitek JL.   +4 more
europepmc   +1 more source