Results 81 to 90 of about 808,169 (217)
How to go viral: A COVID-19 model with endogenously time-varying parameters. [PDF]
Ho P, Lubik TA, Matthes C.
europepmc +1 more source
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Crowding Out or Ricardian Behaviour? Evidence from South Africa
This paper examines whether government debt financing crowds out private consumption in South Africa or whether household behaviour is consistent with Ricardian equivalence.
Kazeem Abimbola Sanusi +1 more
doaj +1 more source
This article presents a time-varying modal parameter identification method based on the novel information criterion (NIC) algorithm and a post-process method for time-varying modal parameter estimation.
Haotian Zhou +4 more
doaj +1 more source
An Estimation Algorithm for General Linear Single Particle Tracking Models with Time-Varying Parameters. [PDF]
Godoy BI, Vickers NA, Andersson SB.
europepmc +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
A Square-Root Second-Order Extended Kalman Filtering Approach for Estimating Smoothly Time-Varying Parameters. [PDF]
Fisher ZF +5 more
europepmc +1 more source
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source
[Design and application of neural electrical stimulation system with time-varying parameters]. [PDF]
Yang G, Feng Z, Zheng L, Wang Z.
europepmc +1 more source

