Results 81 to 90 of about 12,763,216 (315)
The Effect of Statin Use at the Time of Autologous Transplant on Response and Survival in Multiple Myeloma [PDF]
, 2008 Mehdi Hamadani +3 more
openalex +1 more source
External Time–Internal Time [PDF]
Journal of Biological Rhythms, 2002 Daan, S., Merrow, M, Roenneberg, Till
openaire +2 more sources
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Exhaled nitric oxide: time to employ or make redundant? [PDF]
, 2009 Dominick Shaw
openalex +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
A Deep Learning Architecture for Temporal Sleep Stage Classification Using Multivariate and Multimodal Time Series [PDF]
, 2018 Stanislas Chambon +4 more
openalex +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Styrking av helseberedskap og krisehåndtering – «mismatch» mellom samarbeidet i EU og EØS?
Internasjonal PolitikkI EU er helsepolitikk, helseberedskap og krisehåndtering primært et nasjonalt anliggende. Over tid har likevel medlemslandene styrket samarbeidet på disse områdene.
Frode Veggeland, Martin Stangborli Time
doaj +1 more source
Drug Stability Analysis by Raman Spectroscopy
Pharmaceutics, 2014 Pharmaceutical drugs are available to astronauts to help them overcome the deleterious effects of weightlessness, sickness and injuries. Unfortunately, recent studies have shown that some of the drugs currently used may degrade more rapidly in space ...
Chetan Shende +3 more
doaj +1 more source
Integration of circadian and hypoxia signaling via non‐canonical heterodimerization
FEBS Letters, EarlyView.CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley +1 more source