Results 251 to 260 of about 16,940,234 (305)

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

The Eight-Chop Technique in Nonagenarian Patients: Real-World Intraoperative and Postoperative Outcomes. [PDF]

J Clin Med
Sato T.
europepmc   +1 more source

Opposite network patterns of integration-segregation in psychedelic and sedated states of consciousness. [PDF]

Cell Rep
Dai R, Jang H, Hudetz AG, Huang Z, Mashour GA.   +4 more
europepmc   +1 more source

Epidemiological Assessment of Oral and Oropharyngeal Squamous Cell Carcinomas Before, During, and After the COVID-19 Pandemic, 2018-2024. [PDF]

J Clin Med
Alexandru GC, Muntean C, Chioran D, Riviș M, Gligor LN, Pricop MO, Olariu TR.   +6 more
europepmc   +1 more source

Prediction of acute mountain sickness occurring at 4554 m using overnight pulse oximetry from lower altitude: A pilot study. [PDF]

Exp Physiol
Cutts L, Ashdown K, Simpkins C, Trender W, Clarke S, Delamere J, Lucas SJE, Joyce KE.   +7 more
europepmc   +1 more source

Eye-Tracking Evidence for TACOM-Based Assessment of Procedural Task Complexity in a Nuclear Power Plant Full-Scope Simulator. [PDF]

Sensors (Basel)
Xiao H, Li P, Chen W, He J, Tao Z.
europepmc   +1 more source

Time Edisi 10 September 2007 s.d. 24 Desember 2007

, 2009
Time
core