Results 131 to 140 of about 3,283,200 (344)
On Delay-independent Stability of a class of Nonlinear Positive Time-delay Systems
, 2013 We present a condition for delay-independent stability of a class of nonlinear positive systems. This result applies to systems that are not necessarily monotone and extends recent work on cooperative nonlinear systems.Comment: 9 ...
Bokharaie, Vahid, Mason, Oliver
core +1 more source
A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy
Molecular Oncology, EarlyView.Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti +3 more
wiley +1 more source
Delay-Dependent Stability Criteria for Systems with Interval Time-Varying Delay
Journal of Control Science and Engineering, 2011 This paper is concerned with robust stability of uncertain linear systems with interval time-varying delay. The time-varying delay is assumed to belong to an interval, which means that the derivative of the time-varying delay has an upper bound or a ...
Boren Li
doaj +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Synchronization of Time Delayed Fractional Order Chaotic Financial System [PDF]
, 2017 Wei Wei Zhang +3 more
openalex +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
A Class of Shock Wave Solution to Singularly Perturbed Nonlinear Time-Delay Evolution Equations [PDF]
, 2020 Feng Yihu, Lei Hou
openalex +1 more source
, 2018 AbstractDelays often occur between an input into a system and the output from that system. Delays complicate dynamics, create system instabilities, and reduce the information that systems can use to respond to the environment. Adjusting for delays often requires systems to predict future states based on past inputs.
openaire +1 more source
Time-delayed generalized BSDEs
Stochastic Processes and their ApplicationsWe prove the existence and uniqueness of the solution of a BSDE with time-delayed generators in the small delay setting (or equivalently small Lipschitz constant), which employs the Stieltjes integral with respect to an increasing continuous stochastic process.
Di Persio, Luca +3 more
openaire +4 more sources
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source