Results 181 to 190 of about 1,406,233 (296)

Age‐Related Characteristics of SYT1‐Associated Neurodevelopmental Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives We describe the clinical manifestations and developmental abilities of individuals with SYT1‐associated neurodevelopmental disorder (Baker‐Gordon syndrome) from infancy to adulthood. We further describe the neuroradiological and electrophysiological characteristics of the condition at different ages, and explore the associations ...
Sam G. Norwitz, Josefine Eck, Joel S. Winston, Kate Baker   +3 more
wiley   +1 more source

Extreme events in gene regulatory networks with time-delays. [PDF]

Sci Rep
Vinoth S, Kingston SL, Srinivasan S, Kumarasamy S, Kapitaniak T.   +4 more
europepmc   +1 more source

Functional Connectivity Linked to Cognitive Recovery After Minor Stroke

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Patients with minor stroke exhibit slowed processing speed and generalized alterations in functional connectivity involving frontoparietal cortex (FPC). The pattern of connectivity evolves over time. In this study, we examine the relationship of functional connectivity patterns to cognitive performance, to determine ...
Vrishab Commuri, Isabella Dallasta, Ciaran Stone, Sophia Girgenti, Neda Gould, Rafael H. Llinas, Jonathan Z. Simon, Elisabeth Breese Marsh   +7 more
wiley   +1 more source

Time delays in emergency stroke care in a low-resource referral hospital in Ghana. [PDF]

Afr J Emerg Med
Yakubu HA, Marfo RO, Boakye-Yiadom J, Aidoo FM, Sarfo FS, Oteng RA.   +5 more
europepmc   +1 more source

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky, Cara Joyce, H. Jeremy Bockholt, Paul A. Rudnick, William H. Adams, Fiona McAllister, Justin W. Smock, Michael A. Newton, Jane S. Paulsen   +8 more
wiley   +1 more source

DelaySSA: stochastic simulation of biochemical systems and gene regulatory networks with or without time delays. [PDF]

PLoS Comput Biol
Jin Z, Zhou X, Fang Z.
europepmc   +1 more source

Incorporating Time Delays in the Mathematical Modelling of the Human Immune Response in Viral Infections. [PDF]

Procedia Comput Sci, 2021
Dagasso G, Urban J, Kwiatkowska M.
europepmc   +1 more source

Lessons Learned From a Delayed‐Start Trial of Modafinil for Freezing of Gait in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Freezing of gait (FOG) in people with Parkinson's disease (PwPD) is debilitating and has limited treatments. Modafinil modulates beta/gamma band activity in the pedunculopontine nucleus (PPN), like PPN deep brain stimulation. We therefore tested the hypothesis that Modafinil would improve FOG in PwPD.
Tuhin Virmani, Lakshmi Pillai, Reid D. Landes, Aliyah Glover, Shannon Doerhoff, Jennifer Kleiner, Mitesh Lotia, Rohit Dhall, Edgar Garcia‐Rill   +8 more
wiley   +1 more source

Reducing time delays and enhancing reperfusion eligibility related to stroke suspicion by the Emergency Medical Dispatch Centre: a registry-based observational study. [PDF]

Emerg Med J
Leto N, Farbu E, Barach P, Busch M, Lund H, Bjørshol CA, Kurz M, Fromm A, Østerås Ø, Hagen LT, Lindner TW.   +10 more
europepmc   +1 more source

Effect of cellular rearrangement time delays on the rheology of vertex models for confluent tissues. [PDF]

PLoS Comput Biol, 2021
Erdemci-Tandogan G, Manning ML.
europepmc   +1 more source