Results 51 to 60 of about 14,925,506 (231)
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
工程科学与技术, 2022 Landslide deposits are one of the main sources of flash flood and sediment disaster, and their spatio-temporal distribution and evolution characteristics play an important role in the early identification of flash flood and sediment disaster areas and ...
Xinyue YUAN +8 more
doaj
Detection of Atmospheric Water Deposits in Porous Media Using the TDR Technique
Sensors, 2015 Investigating the intensity of atmospheric water deposition and its diurnal distribution is essential from the ecological perspective, especially regarding dry geographic regions. It is also important in the context of monitoring the amount of moisture
Anna Nakonieczna +6 more
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Rivista Italiana di Paleontologia e Stratigrafia, 2010 At Cape Tindari, in North-Eastern Sicily, both right-lateral and extensional displacements are documented, but very little is known about the timing of the Upper Pleistocene faults. On the steep cliffs delimiting Cape Tindari, a triangular shaped fissure
LAURA BONFIGLIO +2 more
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Entangled external and internal controls on submarine fan evolution: an experimental perspective
The Depositional Record, 2020 Submarine fans are formed by sediment‐laden flows shed from continental margins into ocean basins. Their morphology represents the interplay of external controls such as tectonics, climate and sea level with internal processes including channel migration
Ross A. Ferguson +6 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Editorial for Special Issue “Geology of Uranium Deposits”
, 2021 The study of uranium deposits is crucial for the discovery of much-needed new resources of uranium [...
Andy Wilde
core +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source