Results 91 to 100 of about 2,669,999 (264)

FPGA-Microprocessor Based Sensor for Faults Detection in Induction Motors Using Time-Frequency and Machine Learning Methods

Sensors
Induction motors (IM) play a fundamental role in the industrial sector because they are robust, efficient, and low-cost machines. Changes in the environment, installation errors, or modifications to working conditions can generate faults in induction ...
Roque Alfredo Osornio-Rios, Isaias Cueva-Perez, Alvaro Ivan Alvarado-Hernandez, Larisa Dunai, Israel Zamudio-Ramirez, Jose Alfonso Antonino-Daviu   +5 more
doaj   +1 more source

Time-Domain Behavior of Plasmonic Half-Spaces

IEEE Photonics Journal, 2012
The time-domain surface impedance for a plane-wave incidence on a half-space with conductive and plasmonic properties is theoretically investigated. This paper provides closed-form time-domain expressions of time-domain surface impedance values that can ...
M. Stumpf, G. A. E. Vandenbosch
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

FEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Stacked ensemble machine learning approach for electroencephalography based major depressive disorder classification using temporal statistics

Systems Science & Control Engineering
Major depressive disorder (MDD) is a serious and widespread mental health condition that remains challenging to diagnose accurately. Traditional psychological assessments, which can be subjective and sometimes unreliable, emphasize the need for more ...
Nader Nisar Ahmed, Tejas Kadengodlu Bhat, Omkar S. Powar   +2 more
doaj   +1 more source

Method for identifying ageing in epoxy-mica composite insulation used in rotational machines through modelling of dielectric relaxation

High Voltage, 2019
Dielectric response analysis, performed in time domain and frequency domain is one of the interesting methods used for condition assessment of high voltage equipment.
Nikhil Mondal, Nasirul Haque, Sovan Dalai, Sivaji Chakravorti, Biswendu Chatterjee   +4 more
doaj   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source