Results 51 to 60 of about 18,903,950 (247)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Water Science and Engineering, 2010 A dam-reservoir system subjected to an earthquake is a nonlinear system, because the fluid equations are always nonlinear regardless of the linear or nonlinear model used for the dam body. Therefore, transient analysis is necessary.
Quoc Cong Trinh, Liao-jun Zhang
doaj +1 more source
A Time-Domain Analytic Solution of Flow-Induced Undular Bores
Journal of Marine Science and Engineering, 2022 In this study, the problem of surface waves induced by water flow in a flow channel was investigated. The mathematical model based on the potential wave theory was established, and a new analytic solution to the corresponding initial and boundary value ...
Cheng-Tsung Chen +4 more
doaj +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Defect Classification Using Postpeak Value for Pulsed Eddy-Current Technique
Sensors, 2020 In this paper, a feature termed as the postpeak value is proposed for the pulsed eddy current technique (PECT). Moreover, a method using the postpeak value is proposed to classify surface and reverse defects.
Jiuhao Ge +3 more
doaj +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
A Late-time Radio Survey of Type Ia-CSM Supernovae with the Very Large Array
The Astrophysical JournalType Ia-CSM supernovae (SNe) are a rare and peculiar subclass of thermonuclear SNe characterized by emission lines of hydrogen or helium, indicative of high-density circumstellar medium (CSM). Their implied mass-loss rates of ∼10 ^−4 –10 ^−1 M _⊙ yr ^−1 (
Olivia Griffith +10 more
doaj +1 more source
Applied Sciences, 2017 The measurement of the thicknesses of layers is important for the quality assurance of industrial coating systems. Current measurement techniques only provide a limited amount of information.
Samuel Lawman +4 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source