Results 161 to 170 of about 41,285,632 (393)

C9orf72 ALS‐causing mutations lead to mislocalization and aggregation of nucleoporin Nup107 into stress granules

open access: yesFEBS Letters, EarlyView.
Mutations in the C9orf72 gene represent the most common genetic cause of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Using patient‐derived neurons and C. elegans models, we find that the nucleoporin Nup107 is dysregulated in C9orf72‐associated ALS. Conversely, reducing Nup107 levels mitigates disease‐related changes.
Saygın Bilican   +7 more
wiley   +1 more source

Novel and unscrutinized immune entities of the zebrafish gut

open access: yesFEBS Letters, EarlyView.
Understudied cells of the zebrafish immune system include bona fide immune cells and epithelial (‐derived) cells with immune functions. Research focusing on zebrafish cells which demonstrate similarities to mammalian immune cell counterparts may help us understand the pathologies in which they are implicated. Currently available and advanced tools make
Audrey Inge Schytz Andersen‐Civil   +5 more
wiley   +1 more source

QCD-view on hadron form factors in space-like and time-like momentum transfer regions

open access: yes, 2003
QCD gives definite predictions for hadron electromagnetic form factors in space-like and time-like momentum transfer regions, such as the quark counting rules, the hypothesis of hadron helicity conservation, and the relations between nucleon and deuteron
Rekalo, Michail P.   +1 more
core   +1 more source

From lactation to malignancy: A comparison between healthy and cancerous breast gland at single‐cell resolution reveals new issues for tumorigenesis

open access: yesFEBS Letters, EarlyView.
Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona   +4 more
wiley   +1 more source

Psychological, interpersonal, and clinical factors predicting time spent on physical activity among Mexican patients with hypertension

open access: yesPatient Preference and Adherence, 2018
José Luis Ybarra Sagarduy,1 Dacia Yurima Camacho Mata,1 José Moral de la Rubia,2 Julio Alfonso Piña López,3 José Luis Masud Yunes Zárraga4 1Unit of Social Work and Human Development, Autonomous University of ...
Ybarra Sagarduy JL   +4 more
doaj  

Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells

open access: yesFEBS Letters, EarlyView.
Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura   +8 more
wiley   +1 more source

Time of highest tuberculosis death risk and associated factors: an observation of 12 years in Northern Thailand

open access: yesInternational Journal of General Medicine, 2011
Saiyud Moolphate1,2, Myo Nyein Aung1,3, Oranuch Nampaisan1, Supalert Nedsuwan4, Pacharee Kantipong5, Narin Suriyon6, Chamnarn Hansudewechakul6, Hideki Yanai7, Norio Yamada2, Nobukatsu Ishikawa21TB/HIV Research Foundation, Chiang Rai, Thailand; 2Research ...
Saiyud Moolphate   +3 more
doaj  

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