Results 81 to 90 of about 6,758,577 (312)

Comparative Study of Time Taken to Produce Surgical Readiness Between Spinal Anaesthesia and General Anaesthesia for Emergency Caesarean Section

South African Family Practice, 1993
No abstract available.
Hugh A. Brathwaite
doaj   +1 more source

Time-varied factors with significant impacts on effective population size via time^b'*'.

Time-varied factors with significant impacts on effective population size via timeb'*'.
Bas B. Oude Munnink (14019359), Mark Woolhouse (706888), Samantha Lycett (3311286), Emmanuelle Munger (17846768), Styliani Pappa (17846771), Katerina Tsioka (17846774), Anne Pohlmann (505800), Martin Beer (222377), Marion P. G. Koopmans (8703465), Frank M. Aarestrup (7486067), Reina S. Sikkema (10747812), Anna Papa (318166), Barbara B. Shih (11795285), Emanuela Dal Molin (13232094), Rachel A. Taylor (8270871), Ute Ziegler (331024), Alessandro Sinigaglia (519959), Anne Günther (16529393), Frederic Bartumeus (166105), Lu Lu (392), Feifei Zhang (105135), Luisa Barzon (354961)   +21 more
core   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Trends in mortality from gastrointestinal, hepatic, and pancreatic cancers in the United States: A comprehensive analysis (1999–2020)

JGH Open
Background and Aim This study investigates temporal trends in gastrointestinal cancer‐related mortality in the United States between 1999 and 2020, focusing on differences by sex, age, and race. Methods We investigated the Centers for Disease Control and
Hassam Ali, Rizwan Ishtiaq, Brandon Tedder, Joshua Zweigle, Romina Nomigolzar, Dushyant S Dahiya, Vishali Moond, Amir Humza Sohail, Pratik Patel, Debargha Basuli, Hans L Tillmann   +10 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Cardiovascular Risk Factors Associated with Venous Thromboembolism

, 2019
Importance: It is uncertain to what extent established cardiovascular risk factors are associated with venous thromboembolism (VTE). Objective: To estimate the associations of major cardiovascular risk factors with VTE, ie, deep vein thrombosis and ...
Emerging Risk Factors Collaboration
core  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Timing of intervention in cardiogenic shock management: A systematic review and network meta-analysis

Journal of Education and Health Promotion
Cardiogenic shock (CS) is a critical condition with high mortality rates, necessitating timely interventions to optimize patient outcomes. However, the optimal timing for pharmacological and mechanical interventions remains unclear.
Apurva Popat, Sweta Yadav
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source