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In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes +32 more
wiley +1 more source
Unified Theory of Displacement-Covariant Time-Frequency Analysis
Bölcskei, Helmut, Hlawatsch, Franz
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Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman +4 more
wiley +1 more source
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A method for time-frequency analysis
IEEE Transactions on Signal Processing, 1994A method for time-frequency signal analysis is presented. The proposed method belongs to the general class of smoothed pseudo Wigner distributions. It is derived from the analysis of the Wigner distribution defined in the frequency domain. This method provides some substantial advantages over the Wigner distribution.
Ljubisa Stanković
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The beginning of time-frequency analysis
The Journal of the Acoustical Society of America, 2022The Reflections series takes a look back on historical articles from The Journal of the Acoustical Society of America that have had a significant impact on the science and practice of acoustics.
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Discrete-time, discrete-frequency, time-frequency analysis
IEEE Transactions on Signal Processing, 1998Summary: A formulation of a discrete-time, discrete-frequency Wigner distribution for analysis of discrete-time, periodic signals is given using an approach involving group representation theory. This approach is motivated by a well-known connection between group theory and the continuous Wigner distribution.
Michael S. Richman +2 more
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IEEE Signal Processing Magazine, 1999
It has been well understood that a given signal can be represented in an infinite number of different ways. Different signal representations can be used for different applications. For example, signals obtained from most engineering applications are usually functions of time. But when studying or designing the system, we often like to study signals and
Shie Qian, Dapang Chen
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It has been well understood that a given signal can be represented in an infinite number of different ways. Different signal representations can be used for different applications. For example, signals obtained from most engineering applications are usually functions of time. But when studying or designing the system, we often like to study signals and
Shie Qian, Dapang Chen
openaire +1 more source
Time--frequency analysis of biosignals
IEEE Engineering in Medicine and Biology Magazine, 2009The wavelet transform has a powerful time-frequency analysis and signal-coding tool suitable for use in the manipulation of complex nonstationary signals. This article provides an overview of the emerging role of wavelet-transform analysis in biomedical signal processing and analysis.
Addison, Paul +2 more
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